6 results found containing all search terms.
... transcendental nature. Every bacterium and human is a cosmic statement. Shifting from the macroscopic to the microscopic (phenotype to genotype), we recall that all macroscopic "statements" are really expressions of DNA -- the genetic code. But when we examine DNA, we find that only about 3% of the DNA in human cells codes for protein manufacture. The remaining 97% is termed "nonsense" or "junk" DNA. But there may actually be sense in nonsense DNA. Statistical analysis of nonsense-DNA "words" (3 -8 bases long) reveals considerable redundancy. Long stretches of nonsense DNA are definitely not random. In fact, the structure of nonsense DNA resembles that of language. The coding or "sense" DNA, on the other hand, lacks ... Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Unread Biotic Message We have been selling ReMine's book The Biotic Message in which he asserts that life itself is a message of transcendental nature. Every bacterium and human is a cosmic statement. Shifting from the macroscopic to the microscopic (phenotype to genotype), we recall that all macroscopic "statements" are really expressions of DNA -- the genetic code. But when we examine DNA, we find that only about 3% of the DNA in human cells codes for protein manufacture. The remaining 97% is termed "nonsense" or "junk" DNA. But there may actually be sense in nonsense DNA. Statistical analysis of nonsense-DNA "words" (3 -8 bases long) reveals considerable redundancy ...
Terms matched: 2 - Score: 328 - 15 May 2017 - URL: /sf117/sf117p04.htm
... Science Frontiers ONLINE No. 10: Spring 1980 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Dynamic Dna Smugness over our discovery of the genetic code and some simple features of biological synthesis has recently been undermined by the recognition that the so-called nonsense segments in genes may be important after all. Now comes the realization that the DNA molecule may not be a staid, static construction. Travelling kinks and other disturbances seem to play some unknown role in biological recognition. Some biochemists have even suggested that DNA winds and unwinds or "breathes" like a living thing as it helps to manufacture biological substances. (Spencer, Michael; "Bent DNA," Nature, 281:631, 1979.) Comment. The addition of the time ... Science Frontiers ONLINE No. 10: Spring 1980 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Dynamic Dna Smugness over our discovery of the genetic code and some simple features of biological synthesis has recently been undermined by the recognition that the so-called nonsense segments in genes may be important after all. Now comes the realization that the DNA molecule may not be a staid, static construction. Travelling kinks and other disturbances seem to play some unknown role in biological recognition. Some biochemists have even suggested that DNA winds and unwinds or "breathes" like a living thing as it helps to manufacture biological substances. (Spencer, Michael; "Bent DNA," Nature, 281:631, 1979.) Comment. The addition of the time ...
Terms matched: 2 - Score: 260 - 15 May 2017 - URL: /sf010/sf010p07.htm
... to amoeba are merely DNA's way of manufacturing still more DNA -- so goes the modern ramification of molecular biology and the Genetic Code. In other words, DNA and genes are selfish, and ultimate parasites, directing the evolution of life only to maximize the production of DNA. This theme is not the subject of this paper by Doolittle and Sapienza. Rather, they wonder about those nonsense DNA sequences that do not code for protein. The presence of these "useless" bits of genetic material is often explained in terms of gene "expression." Emphasis is always on maximizing the "fitness" of the organism (phenotype). Perhaps this seemingly excess genetic material actually maximizes the fitness (survivability) of the DNA itself. Evolution thus occurs at DNA and gene (genome ... Science Frontiers ONLINE No. 11: Summer 1980 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Hierarchies Of Evolution All organisms from man to mouse to amoeba are merely DNA's way of manufacturing still more DNA -- so goes the modern ramification of molecular biology and the Genetic Code. In other words, DNA and genes are selfish, and ultimate parasites, directing the evolution of life only to maximize the production of DNA. This theme is not the subject of this paper by Doolittle and Sapienza. Rather, they wonder about those nonsense DNA sequences that do not code for protein. The presence of these "useless" bits of genetic material is often explained in terms of gene "expression." Emphasis is always on maximizing the " ...
Terms matched: 2 - Score: 257 - 15 May 2017 - URL: /sf011/sf011p04.htm
... . This wide range of uncertainty does not inspire belief in the accurate readability of this biological blueprint at the present time. Usually left unsaid is the fact that the present blueprint covers only 2-3 % of the territory. That's right, 97-98% of the human genome isn't mapped at all. This uncharted territory is assumed to be "junk" or "nonsense" DNA that plays no role in heredity. Want to bet that this assumption is correct? And don't forget that genes jump around. The genome is really a moving target. Genes also work in concert. It is not one gene coding for one protein, which then has a singular role in creating an operational human being. For example, some 5,692 genes are ... in breast-cancer cells. Genes may also have multiple roles. Our present blueprint of the human genome does not display all the mobility and complex interrelationships of the genes. We do know that genes are the blue-prints for the manufacture of proteins. Of these, there may be over 1,000,000 different -- more than ten times the number of genes! These multitudinous proteins are continually being created and transported to where they perform their assigned tasks and are eventually deconstructed. It is this population of proteins (collectively the "proteome") that develops organisms and gives them life. We do not begin to have a blue-print for the proteome, which really tells us how life works. Then, there are epigenetic influences. "Epigenetic?" Yes, ...
Terms matched: 2 - Score: 218 - 15 May 2017 - URL: /sf131/sf131p07.htm
... infected hamster brains, but no one knows what its normal function is, if indeed it has one. (Anonymous; "Prion Gene," Scientific American, 253:60, July 1985.) Comment. One can make an immediate connection between the traitorous PrP genes in the hamster brains and the excess genetic material in humans and all life forms. Biologists commonly call excess genetic material "nonsense DNA" which only means that they haven't devined its purpose. But, as already sugested, these unused blueprints may have had some past purpose or will be called into action in the future. The purpose may be insidious, as in the case of scrapie, or vital to the organism's survival in some unrecognized biological Armageddons. From Science Frontiers #41, SEP- ... 1985 . 1985-2000 William R. Corliss ...
Terms matched: 2 - Score: 182 - 15 May 2017 - URL: /sf041/sf041p08.htm
... Gesteland and J.F . Atkins, eds., Cold Spring Harbor Laboratory Press, 1993) Nature reviewed the book in its January 20 issue. In addition, the RNA World was discussed recently in Science. We now extract one nugget from each of these two sources. From Nature's review. Humans are more primitive than microorganisms in the sense that we still retain cumbersome introns (nonsense DNA) in our genes, while lowly microorganisms have been able to eliminate them. From Science. No one seems to have a clue about where RNA came from. C. de Duve ventured that: ". .. the emergence of RNA depended on robust chemical reactions -- it is wrong to imagine that some fantastic single accidental event supported the development of the RNA World." ... connection with the generally accepted idea that the evolution of RNA must have taken hundreds of millions of years: ". .. de Duve suggested that, on the contrary, for such a complex chemical process to succeed it must have been relatively fast in order to avoid decay and loss of information." (Brenner, Sydney; "The Ancient Molecule," Nature, 367:228, 1994. O'Neill, Luke, et al; "What Are We? Where Did We Come From? Where Are We Going? Science, 263:181, 1994.) Comment. O.K . There's the RNA World, then came ours. Will another kind of "world" succeed ours? Has it already? From Science Frontiers #92, MAR- ...
Terms matched: 2 - Score: 182 - 15 May 2017 - URL: /sf092/sf092b07.htm
