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No. 24: Nov-Dec 1982

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Mice Transmit Human Gene Sequences To Their Progeny

Viruses habitually subvert the manufacturing facilities of host cells so that they turn out viruses instead of material useful to the host. Stewart and his col-leagues injected fertilized mouse eggs with human beta-globin gene sequences. One of the resulting adult mice carried the human gene sequence intact; one of the others carried at least part of the sequence. More significantly, the latter mouse transmitted the human gene sequence to its progeny in a Mendelian ratio.

(Stewart, Timothy A., et al; "Human Beta-Globin Gene Sequences Injected into Mouse Eggs, Retained in Adults, and Transmitted to Progeny," Science, 217:1046, 1982.)

Comment. Animal cells are therefore not too fastidious about what they manufacture and what is transmitted to progeny. The unanswered questions are: How far can this proxy replication and transmission of genes go; and, most important, can it occur in nature to a degree sufficient to contribute to the evolution of new species?

From Science Frontiers #24, NOV-DEC 1982. 1982-2000 William R. Corliss

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  • "A sourcebook of unexplained phenomena is therefore a valuable addition to a collection of scientific literature. William R. Corliss has provided this in the past with his source books of scientific anomalies in several subjects, and now he has provided it for astronomy. He has done an excellent job of collecting and editing a large amount of material, taken in part from scientific journals and in part from scientific reporting in the popular or semi-scientific press." -- "The Mysterious Universe: A Handbook of Astronomical Anomalies", reviwed by Thomas Gold, Cornell University, in Icarus, vol.41, 1980

  • "An interesting, systematic presentation of unusual weather [..] This book is recommended for a general audience" --"Corliss, William R., Tornados, Dark Days, Anomalous Precipitation, and Related Weather Phenomena, Sourcebook Project, 1983.", revieweed in Choice, September 1983
  • "..the science is necessarily somewhat speculative, but Corliss's symthesis is based on reputable sources." -- "Corliss, William R. (Compiler). Lightning, Auroras, Nocturnal Lights, and Related Luminous Phenomena" reviwed by Joseph M. Moran, Univ. of Wisconsin in Science Books and Films, Sep/Oct 1983

  • "Before opening the book, I set certain standards that a volume which treads into dangerous grounds grounds like this must meet. The author scrupulously met, or even exceeded those standards. Each phenomenon is exhaustively documented, with references to scientific journals [..] and extensive quotations" -- "Book Review: The moon and planets: a catalog of astronomical anomalies", The Sourcebook Project, 1985., Corliss, W. R., Journal of the Royal Astronomical Society of Canada, Vol. 81, no. 1 (1987), p. 24., 02/1987