87 results found.
... Science Frontiers ONLINE No. 8: Fall 1979 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Importance Of Nonsense One of the greatest surprises of modern molecular biology has been the discovery of "split genes" in higher forms of life. In the chromosomes of lowly bacteria, genes march along one behind the other, but in more complex organisms the genes are separated by segments of genetic material that apparently have nothing to do with the manufacture of protein. Because there seems no need for these inserted jumbles of genetic information, they are characterized as "nonsense." But evolutionists insist that this nonsense must have some survival value or it wouldn't be there! Present speculation is that the nonsense segments separate mini-genes that contain the blueprints for assembling well-defined parts of proteins that possess specific functions. To illustrate, the main part of the immunoglobulin molecule has four functional parts (one for interacting with cell membranes, another that functions as a hinge, and so on). Lo and behold, the immunoglobulin gene consists of four mini-genes separated by three segments of nonsense. The suspicion is that the evolution of higher life forms has been accelerated by keeping these prefabricated, functionally oriented mini-genes apart and shuffling them as integral units. The shuffling of entire functional elements rather than smaller bits and pieces of genetic information might speed up organic evolution. (Lewin, Roger; "Why Split Genes?" New Scientist, 82:452, 1979.) From Science Frontiers #8 , Fall 1979 . ...
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... Science Frontiers ONLINE No. 16: Summer 1981 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Hooray, another "dangerous" book!The May 22, 1981, issue of Science devotes three entire pages to a discussion of the issues raised in the book Genes, Minds, and Culture, written by Edward Wilson and Charles Lumsden. The subject of this book is "gene-culture coevolution," which infers that human culture is controlled not so much by "free will" as by rapidly changing human genes. The authors propose that as few as 1000 years are sufficient for important genetic shifts. Such shifts might, for example, impel humans to break out of the Middle Ages and bring on the Industrial Revolution. The most controversial facets of the theory are: (1 ) The tight genetic control over human culture with little room for free will; and (2 ) The rapid blossoming of many cultures as genes shift about. As one scientist remarked, this book is "dangerous." Others describe it as marvelous. The Science article deals not so much with the book as with the reactions to it -- and the reactions have been powerful, both pro and con. (Lewin, Roger; "Cultural Diversity Tied to Genetic Differences," Science, 212:908, 1981.) Comment. The impression one gets from the synopsis of the book is that humankind is diversifying rapidly into new cultural configurations not through human volition but because of those imperious "selfish genes" we all carry. From Science ...
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... Science Frontiers ONLINE No. 18: Nov-Dec 1981 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Descent of man -- or ascent of ape?New Scientist has just published a controversial pair of articles by John Gribbin and Jeremy Cherfas. Summarizing mightily, it seems that: There are no fossils that are unequivocally ancestral to chimpanzees and gorillas but not to man; Therefore, the only good measure of the time when these three species split from one another is the comparison of genetic material; Genetic dating and serological techniques are unanimous in dating the chimp-gorilla-man split at about 5 million years ago. The conclusion that chimpanzees, gorillas, and humans diverged from a com mon ancestor only 5 million years ago is opposed to the widely accepted 20 million years. This conflict in dating is controversial enough, but Gribbin and Cherfas, after considerable fossil analysis, take one more giant step: they suggest that chimps, gorillas, and man descended from an ancestor that was more man-like than ape-like. Chimpanzees and gorillas in this view are descended from man rather than vice versa. (Cherfas, Jeremy, and Gribbin, John; "The Molecular Making of Mankind," and "Descent of Man -- Or Ascent of Ape?" New Scientist, 91:518 and 91:592, 1981.) Comment. This hypothesis is inflammatory enough without our adding more fuel, but the possible connection to the Sasquatch/Abominable Snowman problem should not be overlooked. Reference. The many problems associated ...
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... Science Frontiers ONLINE No. 5: November 1978 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Sunspots And Flu The last six sunspot peaks have coincided with flu pandemics. During the sunspot maxima of 1947, 1957, and 1968, the influenza-A virus underwent anti genic shifts that allowed the virus to bypass the immunity built up in the populace. In 1937, a pandemic occurred but no genetic change was detected, although one might have gone unnoticed. The deadly worldwide 1918-1919 epidemic transpired just after the 1917 sunspot peak and before the discovery of the flu virus. The sunspot maximum of 1928 may have signaled a major shift from the virus causing the 1918-1919 pandemic to the type now afflicting us. (Hope-Simpson, R.E .; "Sunspots and Flu: A Correlation," Nature, 275:86, 1978.) Reference. The curious phenomena of epidemics are cataloged at BHH6 and BHH7 in Biological Anomalies: Humans II. This Catalog is described here . From Science Frontiers #5 , November 1978 . 1978-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 10: Spring 1980 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Dynamic Dna Smugness over our discovery of the genetic code and some simple features of biological synthesis has recently been undermined by the recognition that the so-called nonsense segments in genes may be important after all. Now comes the realization that the DNA molecule may not be a staid, static construction. Travelling kinks and other disturbances seem to play some unknown role in biological recognition. Some biochemists have even suggested that DNA winds and unwinds or "breathes" like a living thing as it helps to manufacture biological substances. (Spencer, Michael; "Bent DNA," Nature, 281:631, 1979.) Comment. The addition of the time dimension to biological synthesis evokes thoughts of oscillating systems, frequency dependence, filters, etc. Perhaps Nature has invented something better than the silicon chip. From Science Frontiers #10, Spring 1980 . 1980-2000 William R. Corliss ...
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... fittest" defensive cells are those that have just the right characteristics to knock off invaders, and only they survive permanently in the body's defensive arsenal, giving it acquired immunity. The Lamarckian part of this story occurs when the RNA of the selected defensive cells gets passed on to the organism's progeny. (Tudge, Colin; "Lamarck Lives -- In the Immune System," New Scientist, 89:483, 1981.) Comment. The picture evolving here is one of a hierarchy of evolutionary struggles -- say, humans on one level and their contained defensive cells on another level. The levels are not completely independent. The question that arises next is whether there are other evolutionary struggles going on, possibly in the mitochondria and chloroplasts, which possess their own genetic material. Or, waxing speculative, are there hierarchies of evolutionary struggle above humanity of which we know nothing except for perhaps a few anomalies representing cross talk between levels? From Science Frontiers #15, Spring 1981 . 1981-2000 William R. Corliss ...
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... . 13: Winter 1981 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Alien Presence Hidden behind an obscure technical title is a most curious discovery. I.C . Eperon and his coworkers at the MRC Laboratory of Molecular Biology, England, have shown that "human mitochondria did not originate from recognizable relatives of present day organisms." The authors go even further, describing human mitochondria as a "radical departure." (Eperon, I.C ., et al; "Distinctive Sequence of Human Mitochondrial Ribosomal RNA Genes," Nature, 286:460, 1980.) Comment. The inferences above may be far-reaching. Mitochondria are vital components in the cells of the so-called higher organisms. Apparently possessing their own genetic material, they are suspected of being descendants of an cient bacteria that invaded and took up residence in cells. If human mitochondria are radically different, could changes in mitochondria be the source of the purported wide gap between humans and other animals? Did the mitochondria change (" evolve") in existing ancient mammals, converting them suddenly into humans? Or did a new "species" of mitochondria infect terrestrial cells, perhaps coming to earth on cosmic debris, as Fred Hoyle has suggested? From Science Frontiers #13, Winter 1981 . 1981-2000 William R. Corliss ...
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... complex, of course, but still devoid of "thinking." Conversely, if humans really do think; that is, transcend preprogramming (free will, if you wish), then bacteria must also think. The third possibility is that at some step in the ladder of life, "higher" life forms begin to think. There is little evidence that life is split so profoundly between thinkers and non-thinkers. (Morowitz, Harold J.; "Do Bacteria Think?" Psychology Today, 15:10, February 1981.) Comment. This ancient controversy about determinism has been revived as: (1 ) Simple life forms have been found to be not-so-simple; (2 ) All life seems unified by a single (or small number of) genetic codes; and (3 ) "Higher" life forms seem more and more to be just composites of simpler, cooperating biological entities. From Science Frontiers #15, Spring 1981 . 1981-2000 William R. Corliss ...
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... not remain true and revert to one or the other of the original species. Although cell fusion has been observed only under laboratory conditions, it seems to represent a near-universal cell phenomenon that might be realized rarely under natural conditions. The implications for the history of life are far-reaching. For example, the mitochondria in human cells that help our bodies use oxygen to obtain energy may well be descendants of bacteria that once fused with primitive cells. The same may be true for the chloroplasts in plant cells. (Thomas, Lewis; "Cell Fusion: Does It Represent a Universal Urge to 'Join Up'?" Science Digest, 86:52, December 1979.) Comment. Natural cell fusion might make large evolutionary steps possible and be much faster than endless small genetic changes. Are we all composite creatures? From Science Frontiers #10, Spring 1980 . 1980-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 13: Winter 1981 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Propagation Of Acquired Characteristics Almost all biologists reject Lamarck's idea that characteristics acquired by a parent can be transmitted to the progeny. In the field of immunology, especially, experimental findings are stimulating a revival of forbidden Lamarckism! Taylor reviews several experiments in which acquired immunity seems to be passed along from generation to generation. This, of course, directly contradicts the Dogma of Evolution and Weissmann's closely related doctrine of the inviolatability of the germ plasm. But Taylor goes on to suggest several ways to circumvent Weissmann's doctrine, the most interesting of which employs viruses to carry acquired genetic information from generation to generation. (Taylor, R.B .; "Lamarckism Revival in Immunology," Nature, 286:837, 1980.) Comment. The possible role of viruses and other "disease carriers" in the unfolding (rather than "evolution") of life is only now being widely recognized. Could it be that the price of evolution and/or the responsiveness of life to environmental pressures is a certain level of infection? From Science Frontiers #13, Winter 1981 . 1981-2000 William R. Corliss ...
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... Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Infections From Comets Astronomer Fred Hoyle notes that pandemics and plagues have generally appeared very suddenly and unexpectedly, sweeping the globe with hard-to-explain swiftness. Noting in passing that comets have always been considered bad omens, he postulates that cometary matter may actually contain bacteria and viruses that infect the earth's populace as the planet passes through cometary tails. Recent spectroscopic studies of interstellar matter and comets themselves indicate a richness of life-associated compounds that infers that outer space might well be the breeding ground of simple life. The authors review some of the strange history of epidemic diseases and wonder if their theory of germbearing comets might not satisfy the data as well as the more common hypothesis of random mutation and genetic recombination. (Hoyle, Fred, and Wickramasinghe, Chandra; "Does Epidemic Disease Come from Space?" New Scientist, 76:402, 1977.) From Science Frontiers #2 , January 1978 . 1978-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 35: Sep-Oct 1984 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects ARE BLUEBLOODS MORE OFTEN TYPE A? In the 1983 issue of Nature (303:522), J.A . Beardmore and F. Karimi-Booshehri reported that, based on a study of a specific British population, A-blood groups are significantly more common among the higher socio-economic groups. As one might predict whenever someone asserts that human success is genetically determined, an avalanche of mail descended on the Nature office. Two other studies that did not show the blueblood effect were offered, although somewhat different populations were involved. Many letters tried to find an explanation for this anomaly in the constitution of the sample. By the time one got to the response by the authors, the whole issue was clouded. (Mascle-Taylor, C.G . N., et al; "Blood Group and Socio-Economic Class," Nature, 309:395, 1984.) From Science Frontiers #35, SEP-OCT 1984 . 1984-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 139: Jan-Feb 2002 Other pages Home Page Science Frontiers Online All Issues Last Issue Next Issue Sourcebook Project Sourcebook Subjects Contents Archaeology Who Needs Boats Confusion that's Hard to Cut Through Astronomy The Spheres can Dance to Convoluted Music White Mars? Ghostly Martian "Forrests" Biology How the Genome's Message can be Altered The Second Genetic Code and Apparently a Third The Mysterious First Green Egg Geology When the Edges of the Continents were Naked Unstable Earth Really High Oysters Geophysics Surf's Up on Californian Shores: Really up at Cortes Bank Tunguska: An Inside Job? Rock-fall Air Blasts Psychology And the Machines Wept for Man ...
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... to the eggs, etc. (SF#78) Selfish DNA. Where animals are merely mechanisms by which DNA perpetuates itself and expands its domain. In other words, DNA calls the shots -- not us! (SF#11) Now we learn about "gene wars." As is well known, genes are thought to control much of what goes on in a living organism. But are they only carriers of hereditary information? Not according to a long, very technical paper by L.D . Hurst et al. It seems that, like selfish DNA, genes have their own agendas. The insidiousness of this is seen in the first sentence of the paper's abstract: "Self-promoting elements (also called ultraselfish genes, selfish genes, or selfish genetic elements) are vertically transmitted genetic entities that manipulate their "host" [as in "us'] so as to promote their own spread, usually at a cost to other genes within the genome." You may not sense it, but your genes are struggling with each other, and you and/or your progeny will carry out the dictates of the victors of the "gene wars." (Hurst, Laurence D., et al; "Genetic Conflicts," Quarterly Review of Biology , 71:317, 1996.) Comment. Given the power that these "selfish genetic elements" can exert on our bodies, it is but a short step to imagining that they can also direct the course of evolution in ways favorable to their agendas. In this interpretation ...
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... Science Frontiers ONLINE No. 122: Mar-Apr 1999 Other pages Home Page Science Frontiers Online All Issues Last Issue Next Issue Sourcebook Project Sourcebook Subjects Contents Archaeology The mosier mounds El nino -- bueno? The black pyramids Astronomy Our lucky star Ghost galaxies Is a singularity worse than a spinning cosmos? Biology Are we running on martian time? Another skin shedder A GENETIC DISCONNECT Another sucker Geology The earth hums more loudly in the afternoons Geophysics Bizarre phsiological effects of lightning Unusual wave Psychology Exceptional human experiences A FEW POTENTIAL EHEs Unclassified A REALLY MEANINGFUL COINCIDENCE Ach du lieber himmel Now we know why! ...
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... . 107: Sep-Oct 1996 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Subversive Cancer Cells It has been generally believed that most cancers originate in a single founder cell, which then multiplies to create the tumor. But cancer is more insidious than expected. A precancerous founder cell may actually subvert nearby noncancerous cells and turn them into cancerous cells. In this sense, the first precancerous cell recruits and transforms healthy cells, enlisting them in its destructive operations, and thereby turning them against the body that produced them. No one yet knows how this subversion is effected or how it evolved. (Why is there cancer anyway?) The basis for this claim involves a few rare human mosaics, whose bodies are built of cells with two different genetic complements. Cancers in human mosaics have been found to contain both types of cells and, therefore, did not grow from a single cell alone. (Day, Michael; "Cancer's Many Points of Departure," New Scientist, p. 16, June 1, 1996) Comments. Curiously, some "primitive" animals, such as sharks, seem to have evolved defenses against cancer that mammals lack. With reference to "mosaics," see item in SF#105 on "Mixed-Up People." Also relevant is BHH25 "' Insidious' Properties of Cancer Metastases" in Humans II . For information on this book, visit here . From Science Frontiers #107, SEP-OCT 1996 . 1996-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 117: May-June 1998 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Unread Biotic Message We have been selling ReMine's book The Biotic Message in which he asserts that life itself is a message of transcendental nature. Every bacterium and human is a cosmic statement. Shifting from the macroscopic to the microscopic (phenotype to genotype), we recall that all macroscopic "statements" are really expressions of DNA -- the genetic code. But when we examine DNA, we find that only about 3% of the DNA in human cells codes for protein manufacture. The remaining 97% is termed "nonsense" or "junk" DNA. But there may actually be sense in nonsense DNA. Statistical analysis of nonsense-DNA "words" (3 -8 bases long) reveals considerable redundancy. Long stretches of nonsense DNA are definitely not random. In fact, the structure of nonsense DNA resembles that of language. The coding or "sense" DNA, on the other hand, lacks this language structure. The implication is that coding and nonsense DNAs carry different kinds of messages. The former consists simply of blueprints; the latter is couched in a language that we have not yet learned to read. (Flan, Faye; "Hints of a Language in Junk DNA," Science, 266:1320, 1994.) Comment. On the microscopic level, we can read only 3% of the biotic message! From Science Frontiers #117, MAY-JUN 1998 . 1998 ...
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... Science Frontiers ONLINE No. 115: Jan-Feb 1998 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Genes vs. memes Vital to the concept of "gene wars" (mentioned in SF#114) is the assumption that our destiny is controlled by "selfish genes" (or "selfish DNA"). The idea that evolution works only at the gene level has been championed by R. Dawkins, and today it dominates much evolution philosophy. However, this "genetic imperialism" is now being challenged by some scientists who insist that culture also affects an organism's evolution, be it a human or an insect. In fact, it was Dawkins himself who first proposed the term "meme" for the cultural counterpart of the gene. A meme, in other words, is an "element" of culture that can be passed along to progeny by imitation and/or cultural pressures. In reductionist thinking, environmental challenges are met by gene mutations plus natural selection. In meme theory, the same challenges are confronted by cultural changes (meme "mutation") plus natural selection. The meme approach is holistic rather than reductionist and is appealing because it allows us some control over our destiny. There are several phenomena in which some scientists profess to see memes overpowering the genes: Generations of female infanticide have led to more male births than female births. In dairy-farming societies, 90% of the population has the enzyme lactase that allows individuals to digest cows' milk. In other societies, 80% ...
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... difficult to separate individual units of life. To illustrate, some fungi may be 1,000 years old and extend for 35 acres (15 hectares) and yet possess a single, still unmodified genome. In his review of A. Rayner's new book Degrees of Freedom: Living in Dynamic Boundaries , T. Wakeford writes: "So, like the World Wide Web, a fungal network is decentralized. There is no central region capable of exerting control over the rest of the network. Rayner's own work suggests that the growth patterns of fungal filaments are forged as much by the environment that they encounter as by their genes. He believes that epigenetics, the process whereby opportunities in an organism's surroundings dictate which genes are expressed, is the norm in microorganisms. Genetic determinism is thus turned on its head." (Wakeford, Tom; "We Are the Fungus," New Scientist, p. 49, May 10, 1997.) Comment. Looking at the above situation from an information viewpoint, as one must these days, it seems that the environment can somehow "interpret" genes as the situation demands. In other words, genes are not "single-message" information carriers, but can be "read" in different ways according to the environment encountered by their "carriers"; that is, the organisms that bear them. Is this how "adaptive evolution" works? If it is, the genome must contain a multitude of "contingency plans" because the environment by itself cannot add a new suite of capabilities to ...
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... Science Frontiers ONLINE No. 92: Mar-Apr 1994 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The World Before Our World Genetically speaking, modern terrestrial life is bilingual in the sense that it employs two chemical languages. Function is written in the 20 amino-acid "alphabet" of proteins, while information is conveyed in sequences of four nucleotide "letters" called codons. We need go no further with the genetics lesson because our purpose here is to speculate a bit about the monolingual world that is believed to have preceded ours. This older world is commonly termed the "RNA World." It was and is monolingual because both function and information are carried on a single molecule. It is customary to call the RNA World "prebiotic," meaning that it was all chemistry and no life. But, one does wonder whether that was all there was to it. Catalysis and replication of genetic information occurred in the RNA World. What besides a chemical soup might have existed before "life-as-we-know-it" arrived upon the scene? A science fiction writer like H.P . Lovecraft could certainly come up with an ominous entity based upon RNA alone. Be that as it may, a book is now on the market bearing the title The RNA World (R .F . Gesteland and J.F . Atkins, eds., Cold Spring Harbor Laboratory Press, 1993) Nature reviewed the book in its January 20 issue. In addition, the RNA World was discussed recently in ...
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... Science Frontiers ONLINE No. 100: Jul-Aug 1995 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects When Humans Were An Endangered Species At one point during the last 400,000 years, the human population worldwide was reduced to only about 10,000 breeding men and women -- the size of a very small town. What caused this population "bottleneck"? Did a population crash engulf the entire globe. If not, who was spared? Such questions arise from a surprising observation: Human DNA is remarkably uniform everywhere humans are found. This hidden genetic uniformity is difficult to believe if one strolls through a cosmopolitan city like New York or Paris. Nevertheless, compared to the DNA of the great apes, whose mutation rates should be close to ours, human genes on the average show far fewer mutations. Human DNA from Tokyo and London is more alike than that from two lowland gorillas occupying the same forest in West Africa. Harvard anthropologist M. Ruvolo has commented: "It is a mystery that none of us can explain." The clear implication is that humans recently squeezed through a population bottleneck, during which many accumulated mutations were wiped out. In a sense, the human race began anew during the last 400,000 years. Unfortunately, DNA analysis cannot say where the very grim reaper came from. (Gibbons, Ann; "The Mystery of Humanity's Missing Mutations," Science, 267:35, 1995.) Comment. The hand that wiped the slate clean, or nearly so ...
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... might reignite speculation that earth life might not be unique after all. (Travis, John; "Hints of First Amino Acid outside Solar System," Science, 264:1669, 1994.) Structure of the amino acid glycine What Science did not mention but New Scientist did is that F. Hoyle and C. Wickramasinghe have long predicted that the molecules of life, as well as life itself, would be found in outer space. Now, after much ridicule, they are being vindicated. "It's been a long hard struggle," said Hoyle. Wickramasinghe remarked that the discovery was "no surprise at all." "He believes it is only a matter of time before other amino acids, together with nucleotide bases, the components of nucleic acids that make up genetic material, are found in space. 'This is just the tip of the iceberg,' he says. 'I would fully expect a vast array of life molecules to be discovered in space, and then there would be no doubt as to where terrestrial life began.'" (Hecht, Jeff; "' Molecule of Life' Is Found in Space," New Scientist, p. 4, June 11, 1994.) Comment. Here is a case where a scientific prediction was made, but its author labelled heretical. It is a scientific victory, but we guess that Hoyle and Wickramasinghe are too iconoclastic for Science to give them credit for their prediction. From Science Frontiers #95, SEP-OCT 1994 . 1994-2000 William R. Corliss ...
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... Subjects Our genes aren't us!Almost without exception, biology textbooks, scientific papers, popular articles, and TV documentaries convey the impression that an organism's genes completely specify the living animal or plant. In most people's minds, the strands of DNA are analogous to computer codes that control the manufacture and disposition of proteins. Perhaps our current fascination with computers has fostered this narrow view of heredity. Do our genes really contain all the information necessary for constructing human bodies? In the April 1994 issue of Discover, J. Cohen and I. Stewart endeavor to set us straight. The arguments against the "genes-are-everything" paradigm are long and complex, but Cohen and Stewart also provide some simple, possibly simplistic observations supporting a much broader view of genetics. Mammalian DNA contains fewer bases than amphibian DNA, even though mammals are considered more complex and "advanced." The implication is that "DNA-as-a -message" must be a flawed metaphor. Wings have been invented at least four times by divergent classes (pterosaurs, insects, birds, bats); and it is very unlikely that there is a common DNA sequence that specifies how to manufacture a wing. The connections between the nerve cells comprising the human brain represent much more information than can possibly be encoded in human DNA. A caterpillar has the same DNA as the butterfly it eventually becomes. Ergo, something more than DNA must be involved. [This observation does seem simplistic, because DNA could, in principle, code for metamorphosis.] Like DNA ...
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... "; that is, mutations are random and unrelated to the biological needs for survival. This assumption is enshrined in R. Dawkins' book The Blind Watchmaker . Catchy though this title is, it looks more and more like the Watchmaker sees something. For over a decade, experiments have hinted that those mutations that are helpful to an organism's survival occur more often than those that are not "adaptively useful." This controversial phenomenon is termed "adaptive mutation." (SF#64 and SF#96*) A recent issue of Science presents two more papers that seem to confer the gift of sight on the old Watchmaker. Biochemist J.A . Shapiro, in a commentary accompanying the two Science papers, highlights a significant feature of adaptive mutation in bacteria: The genetic changes involved are multicellular. In other words, DNA rearrangements in one cell are actually transferred to other cells. But most profound of all for the whole science of biology is his sentence: "The discovery that cells use biochemical systems to change their DNA in response to physiological inputs moves mutation beyond the realm of 'blind' stochastic events and provides a mechanistic basis for understanding how biological requirements can feed back onto genome structure." (Shapiro, James A.; "Adaptive Mutation: Who's Really in the Garden?" Science, 268:373, 1995.) Comment. Random mutation has been a linchpin of Neo-Darwinism because it is "scientific"; that is, non-supernatural. We see in adaptive mutation that other scientific mechanisms may indeed exist ...
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... Science Frontiers ONLINE No. 91: Jan-Feb 1994 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Dna Undermines Key Paradigms Lately, the Wall Street Journal has expanded its coverage from stocks and bonds to the Marfa lights and other scientific anomalies. Now, it is challenging archeological sacred cows using mitochondrial DNA. Quite a switch from pork futures! Of course, the WSJ is not a recognized scientific source, but its reporter did get his information directly from D.C . Wallace, a well-known professor of genetics and molecular medicine at Emory University and a champion of the African Eve theory. Surely an unusual illustration for the archeology section, but the DNA in these mitochondria may upset long-held theories of human migration. Anyway, Wallace has been studying mitochondria, those little energizers in human and animal cells. Strangely, mitochondria have their own DNA, which is separate and distinct from the nuclear DNA that directs other biological processes. Mitochondrial DNA has had its own history of evolution and is different for various human populations. Wallace has used this fact to trace the origins of American Indians by comparing their mitochondrial DNA with that from Asians, Africans, etc. His conclusions are controversial to say the least. The Amerinds, who comprise most of the Native Americans, arrived in a single migratory wave 20,000-40,000 years ago -- not merely 12,000 years ago! Native Siberians lack a peculiar mutation of mitochondrial DNA that appeared in the Amerinds 6,000-10,000 years ago ...
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... Science Frontiers ONLINE No. 77: Sep-Oct 1991 Other pages Home Page Science Frontiers Online All Issues Last Issue Next Issue Sourcebook Project Sourcebook Subjects Contents Archaeology PLIOCENE SCULPTURES OR FREAKS OF NATURE? A PAPER TRAIL FROM ASIA TO THE AMERICAS Astronomy Mercury: the impossible planet Eclipse shadow-band anomalies Biology Supernova theory exploded NO UNKNOWN MONSTERS IN THOSE FIJI UNDERWATER CAVES: NEVERTHELESS, THE MYSTERY DEEPENS DO BIRDS USE GENETIC MAPS DURING MIGRATION? Cooler heads, bigger brains? The aye-aye, a percussive forager identical Geology VALLEYS OF DEATH AND ELEPHANT GRAVEYARDS Anthracite man? METHANE HYDRATE: PAST FRIEND OR FUTURE FOE? The gruyerizaton of switzerland faulting Geophysics CROP CIRCLES: DAISY PATTERNS AND A RED BALL OF LIGHT Hovering ball of fire SOME OLD GEYSERS ARE NOT SO FAITHFUL WATER'S MEMORY OR BENVENISTE STRIKES BACK Physics Drip, drop, drup, dr** ...
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... Science Frontiers ONLINE No. 41: Sep-Oct 1985 Other pages Home Page Science Frontiers Online All Issues Last Issue Next Issue Sourcebook Project Sourcebook Subjects Contents Archaeology The Australian Pyramids The Inka Road System California Skeletons Not So Old After All Astronomy Galaxy Redshifts Come in Clumps Wimps in the Sun? Biology An Animal That Photosynthesizes The Deceitful She-males Scrapie Transmitted by Prions Latest Episode: Loch Ness Evolution's Motor Runs Fast and Quietly Genetic Garrulousness Death and Social Class Geology Anatomy of A Magnetic Field Reversal Did the Australites Fall Recently? Geophysics Green Sky Flashes Ball Lightning Strikes Twice! Chemistry & Physics All Things Appear to Those Who Accelerate A Possible Crack in the Wall of the Temple of Relativity Restless Gold Unclassified Blinded by the Night ...
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... Science Frontiers ONLINE No. 40: Jul-Aug 1985 Other pages Home Page Science Frontiers Online All Issues Last Issue Next Issue Sourcebook Project Sourcebook Subjects Contents Archaeology Standing-stone Cluster in Eastern Massachusetts Megalithic Recycling Astronomy Planets As Sun-triggered Lasers Neptune's Arcs: Embryonic Moons? Next Let Us Consider Uranus What is It? A Black Hole, of Course! Biology Nessie Photos Not Retouched Frog Mothers Do So Care! Glitch in the Evolution of Funnelweb Spider Venom? Circadian Rhythms and Chemotherapy Genetic Code Not Universal! Geology Back to Guadeloupe Again Galapagos Younger Than Thought Libyan Desert Glass May Not Be the Product of Impacts. Geophysics Quakes and UFOs Vanishing Goo Multiple Whirlwind Patterns Psychology Mnemonism Not So Easy! Hypnotic Misrecall Chemistry & Physics Fruitfulness of Math Not An Intimation of A Transcendent Mind! The Most Profound Discovery of Science Messengers of A "new Physics" Double Nuclei At Darmstadt ...
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... Science Frontiers ONLINE No. 139: Jan-Feb 2002 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Second Genetic Code And Apparently A Third Genes may or may not be switched on depending upon the addition of molecules called "methyl groups" to DNA. Now, a second kind of gene switch has been discovered on histones, a class of proteins. Figuring out when methylation of histones takes place has far-reaching implications; acting as a second genetic code, histone methylation may determine genetic traits such as the susceptibility to disease. (Martindale, Diane; "Genes Are Not Enough," Scientific American, 285:22, October 2001.) Comment. So, beyond the first genetic code (the DNA) and the second genetic code (the recognized methyl groups), we now have some proteins (the histones) getting in on the act. And the show ain't over yet! From Science Frontiers #139, Jan-Feb 2002 . 2001 William R. Corliss Other Sites of Interest SIS . Catastrophism, archaeoastronomy, ancient history, mythology and astronomy. Lobster . The journal of intelligence and political conspiracy (CIA, FBI, JFK, MI5, NSA, etc) Homeworking.com . Free resource for people thinking about working at home. ABC dating and personals . For people looking for relationships. Place your ad free. ...
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... Science Frontiers ONLINE No. 127: Jan-Feb 2000 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects A FAR-WANDERING TRIBE?" The Lemba, a Bantu-speaking people of southern Africa have a tradition that they were led out of Judea by a man named Buba. They practice circumcision, keep one day a week holy and avoid eating pork or piglike animals." As the author of the above words, N. Wade, is quick to point out, there are several other groups of people around the world who practice Judaic rites or claim to be of Jewish ancestry but have no provable ancestral connections. The Lemba, however, also have a genetic tie. Lemba males carry a distinctive set of genetic mutations in their Y chromosomes. This particular genetic characteristic is strongly associated with the cohanim, the Jewish priests said to be descendants of Aaron. This genetic trait is less common among lay Jews (only 3-5 %) and very, very rare among non-Jews. This "cohen genetic" signature (cohen = priest) is considered diagnostic of populations of Jewish ancestry. (Wade, Nicholas; "DNA Confirms Jewish Ancestry of African Tribe," Houston Chronicle, May 10, 1999. Cr. D. Phelps. Anonymous; "DNA Ties African Group to Jews," Chicago Sun-Times , May 10, 1999. Cr. J. Cieciel) From Science Frontiers #127, JAN-FEB 2000 . 1997 William R. Corliss ...
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... mtDNA clock run more slowly. So, African Eve, if she ever existed, is probably twice as old as originally thought. (Day, Michael; "All about Eve...," New Scientist, p. 4, March 13, 1999.) Maybe There Were Two Eves! Not only has African Eve aged precipitously but there may have been a non-African Eve, too. J. Hey and E. Harris, at Rutgers, have presented data suggesting that the famous African Eve was the mother of only modern sub-Saharan Africans. Everyone else seems to have descended from an entirely different Eve. These data, if confirmed, demolish the African Eve theory and support the often-reviled multiregional theory of humans origins. (Pennisi, Elizabeth; "Genetic Study Shakes Up Out of Africa Theory," Science, 283:1828, 1999. Bower, B.; "DNA Data Yield New Human-Origins View," Science News, 155:181, 1999.) Genetic Clocks Are Fickle. mtDNA clocks have implied that modern birds and mammals were contemporaneous with dinosaurs, and that some animals evolved millions of years before their first fossils. For good reasons, evolutionists are becoming wary about these molecular clocks. It is fast becoming obvious that: "Clocks tick at different rates in different lineages and at different times. And new work on the biology of mitochondria suggests that their evolution may be more complicated than researchers had suspected." (Strauss, Evelyn; "Can Mitochondrial Clocks Keep Time?" Science, 283:1435 ...
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... Science Frontiers ONLINE No. 139: Jan-Feb 2002 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects How The Genome's Message Can Be Altered Our genomes (complements of genes) can no longer be called sets of instructions like those in a computer program. Demonstrating the veracity of this statement are the following three quotations. Increasingly, a picture of interactivity and multifunctionality among genes is emerging that precludes such a simple one-to-one mapping. Furthermore, the genome can exhibit considerable flexibility to adapt when the expression of a particular gene fails, and the interpretation of a mutant phenotype [life form] is also less trivial than it may seen. "Not only are behavioural phenotypes very sensitive to non-genetic influences," writes [R .] Greenspan, "but also the highly interconnected network of the nervous system sets up an additional layer of complexity between the gene and the realization of the phenotype." (Ref. 1) Many genes code for multiple variants of the same protein. And many proteins are modified by adding sugar molecules, which play a big role in determining where proteins go and what they do. What's more, different proteins can join together to carry out completely new functions. (Ref. 2) A group of French biologists, led by Francois Jacob and Jacques Monod showed that the gene's boundaries are fuzzier than had been thought and that genes are not restricted to chromosomes. Recently, biologists have found genes within genes, overlapping genes, and DNA sequences that ...
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... self-tickle is hard to understand. After all, we can easily produce a knee-jerk reaction by tapping our own knee. Why can't we tickle our own ribs? Perhaps because our brain controls the action and also cancels out signals to pull away from the tickle and laugh. It could be the unpredictability of someone else's tickling that makes it so effective. Yet, when the tickler tickles our shoulder rather than our ribs, nothing happens. Strange! Why would evolution have given humans highly specific ticklish areas that respond only to other people and, to boot, makes us laugh? What survival value is there in this? In the end, Harris has to admit that tickling may not be adaptive at all, but rather an almost-neutral side effect genetically linked to some different characteristic that is adaptive. Mother Nature's joke on us? (Harris, Christine R.; "The Mystery of Ticklish Laughter," American Scientist, 87:344, 1999.) From Science Frontiers #126, NOV-DEC 1999 . 1999-2000 William R. Corliss ...
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... morning, he took a shine to a young woman he saw taking her small son to a nursery. The got talking, and within months the three were living together. "Then friends began to comment on how little Misha was the splitting image of his new father, and the local optometrist remarked that the boy had inherited his minor eye condition. Their words set Mr. Gusiyev's mind racing -- and apparently led to the discovery that there really was a family resemblance. He had fathered the child by donating sperm at the local fertility clinic in the town of Yaroslav." Gusiyev's new girl friend was a divorcee who had been married to an impotent man. She and her former husband had agreed to the artificial insemination before their divorce. A likely story? Genetic fingerprinting proved that Gusiyev was indeed the father of the child. As for the happy ending, Gusiyev and girl friend were soon married. (Blundy, Anna; "Fatherhood Takes on New Meaning for Sperm Donor," London Times, December 31, 1998. Cr. A.C .A . Silk.) From Science Frontiers #122, MAR-APR 1999 . 1999-2000 William R. Corliss ...
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... Songbirds? BBC7 Are Birds More Closely Related to Mammals Than to Reptiles? BBC8 The Inability of Some Birds to Synthesize Ascorbic Acid BBD DISTRIBUTION OF BIRDS IN SPACE AND TIME BBD1 Discontinuous Populations of Birds BBD2 Uncolonized Areas: Unfilled Niches BBD3 Land Birds Observed Far at Sea BBD4 Late Survival of Moas and Passenger Pigeons BBD5 Distribution Curiosities BBE THE FOSSIL RECORD OF BIRDS BBE1 The Fossil Record of Birds and Associated Paradigms BBE2 Evidence against the Dinosaur Origin of Birds BBE3 Protoavis: A Pre-Archaeopteryx Bird? BBE4 Unresolved Nature of Archaeopteryx BBE5 The Apparent Absence of Transitional Forms of Feathers BBE6 Fossils of Ostrich Ancestors in the Northern Hemisphere BBE7 Controversial Feathers of the London Archaeopteryx Fossil BBE8 Giant Fossil Eggs BBF BODILY FUNCTIONS BBF1 The Avian Respiratory System: Unique, Complex, Sophisticated BBF2 Avian Bodily Functions: Some Oddities BBG GENETICS BBG1 Species mtDNA More Diverse Than Morphology BBG2 Discordance in the Date of Divergence of Modern Birds BBG3 Discordances between Phylogenies Established from Morphology and DNA Analysis BBG4 Dearth of Introns in Birds BBI INTERNAL STRUCTURES AND SYSTEMS BBI1 Avian Magnetoreceptors: Hard to Find BBI2 Curious Internal Structures BBO ORGANS BBO1 Complexity and Sophistication of Some Owl Ear-Brain, Sound-Localization Systems BBO2 Regeneration of Brain Neurons BBO3 Curiosities of Avian Brains BBO4 The Pecten: A Unique Structure in the Avian Eye BBO5 Curiosities of Avian Eyes BBO6 High Complexity and Sophistication of the Avian Eye BBO7 Remarkable Tongue Adaptations BBO8 The Loss and Reduction of Reproductive Organs BBT UNUSUAL TALENTS AND FACULTIES BBT1 Infrasound and Atmospheric Pressure-Change Detection BBT2 Utility of Ultraviolet Vision in Birds BBT3 Echolocation: Parallel Evolution in Birds BBT4 Navigational Feats during Migration BBT5 Homing: Release ...
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... Science Frontiers ONLINE No. 122: Mar-Apr 1999 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects A Genetic Disconnect Bandings on chromosome 9 from humans (H ), chimpanzees (C ), gorillas (G ), orang-utans (O ) If human and chimpanzee nuclear DNAs differ by only 1.5 %, why are the two species so profoundly different in anatomy and behavior? The obvious external differences are body hair, the use of language, the method of locomotion, and of course culture. Less well known is the fact that humans are more susceptible to diseases like as cancer and AIDS. Apparently, superficial comparisons of DNAs slough over genetic details that result in major differences in the living animals. Some of the genetic differences between humans and chimps seem to belie that miniscule 1.5 % difference everyone bandies about. To illustrate, humans have only 46 chromosomes, while the great apes all have 48. The 1.5 % figure doesn't hint at this significant difference. Next, take a look at chromosome #9 in humans and the great apes. Chromosome bandings are different enough to raise further suspicions about the 1.5 % figure. (Gibbons, Ann; "Which of Our Genes Make Us Human?" Science, 281:1432, 1998.) Comments. It is easy to see how gross comparisons of DNA might miss important details. The popular "DNA-hybridization" method simply mixes together strands of DNA from the two species being compared. These are allowed ...
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... tend to forget that the earth's atmosphere, its oceans, and the solid crust to unknown-but-great depths are colonized in profusion by minute biological entities -- mainly bacteria and viruses. Only when we get the flu or infected finger do these entities impinge upon our consciousness. Below we will learn that there are many more of them than you think. Do viruses control the oceans? You may avoid the beaches after you learn that one teaspoon of seawater typically contains 10-100 million viruses and onetenth that many bacteria. Obviously, most are harmless to humans. However, the viruses do infect the bacteria and phytoplankton, destroying them, and thereby releasing their nutrients. By doing this, they keep the oceans' biological engines running. Further, the viruses act as genetic engineers as they transfer DNA from one individual to another. The oceans may be viewed as vast test tubes in which biodiversity is maintained by teeming, invasive viruses. (Suttle, Curtis A.; "Do Viruses Control the Oceans?" Natural History, 108:48, February 1999.) We are only 10% human! The average human body contains 100 trillion cells, but only 1 in 10 of these cells is your own. The remaining 90% are bacteria. These alien organisms coat your skin and pave your inner passageways from mouth to anus. Of course they are much smaller than your own cells, so what you see is mostly you. Even so, you are a composite creature and cannot survive without these tiny hitchhikers and symbionts. Just as in the ...
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