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... Bone shedders * Skin shedders * "Perfection" of the eye * Dearth of memory traces * Sudden increase of hominid brain size * Health and the weather * Periodicity of epidemics * Extreme longevity * AIDS anomalies * Cancer anomalies * Human limb regeneration * Nostril cycling * Voluntary suspended animation * Male menstruation [Picture caption: Is the complexity of the human eye anomalous?] 297 pages, hardcover, $19.95, 40 illus., 3 indexes, 1993. 494 references, LC 91-68541, ISBN 0-915554-27-5 , 7x10. Biological Anomalies: Humans III: A Catalog of Biological Anomalies Sorry, Out of print Completing our trilogy on human anomalies, this volume focuses on four areas (1 ) the human fossil record; (2 ) biochemistry and genetics; (3 ) possible unrecognized living hominids; and (4 ) human interactions with other species and "entities " Typical subjects covered: Neanderthal demise * Giant skeletons * Tiny skeletons * Hominid gracilization * Sudden brain expansion * Human chimeras * Sasquatch / Bigfoot, Alma, Yeti, and others * Human-animal communication * Humanity and Gaia * Anomalous distribution of human lice Comments from reviews: "Some fascinating thinking om the frontiers of science", Borderlands. 212 pages, hardcover, $19.95, 44 illus., 3 indexes, 1994. 311 references, LC 91-68541. ISBN 0-915554-29-1 , 7x10. Biology Handbook For a full list of biology subjects, see here . Biological Anomalies: Mammals I: A Catalog of Biological Anomalies ...
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... Science Frontiers The Book Strange reports * Bizarre biology * Anomalous archaeology From New Scientist, Nature, Scientific American, etc Archaeology Astronomy Biology Geology Geophysics Mathematics Psychology Physics Science Frontiers The Book Contents Science Frontiers is an indexed compilation of the first 86 issues of our Science Frontiers newsletter . Chapter 1. Archeology: Ancient Engineering Works * Small Artifacts * Epigraphy and Art * Bones and Footprints * Diffusion and Culture. Chapter 2. Astronomy: Planets and Moons * Solar System Debris * Stars * Galaxies and Quasars * Cosmology. Chapter 3. Biology: Humans .* Other Mammals * Birds * Reptiles and Amphibians * Fish * Arthropods * Invertebrates * Plants and Fungi * Microorganisms * Genetics * Origin of Life * Evolution. Chapter 4. Geology: Topography * Geological Anomalies * Stratigraphy * Inner Earth. Chapter 5. Geophysics: Luminous Phenomena* Weather Phenomena * Hydrological Phenomena * Earthquakes * Anomalous Sounds * Atmospheric Optics. Chapter 6. Psychology: Dissociation Phenomena * Hallucinations * Mind - Body Phenomena * Hidden Knowledge * Reincarnation * Information Processing * Psychokinesis. Chapter 7. Chemistry, Physics, Math, Esoterica: Chemistry * Physics * Mathematics. Comments from reviews: "This fun-to-read book may lead some to new scientific solutions through questioning the phenomena presented", Science Books and Films Publishing details: 356 pages, paperback, $18.95, 417 illus., subject index, 1994. 1500+ references, LC 93-92800 ISBN 0-915554-28-3 , 8.5 x 11. Order From:The Sourcebook Project P.O . Box ...
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... 2000 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects A Third Way?A THIRD WAY? In the never-ending, ever-acrimonious "dialog of the deaf" between the Darwinists and the Creationists, we are perpetually exposed to their extreme, non-negotiable positions. The Darwinists insist upon their one-gene/one-protein genome in which random mutations slowly accumulate and adapt living things to the changing environment. The Creationists only accept a one-time, supernatural creation of "kinds" plus minor adaptations (" microevolution"). J.A . Shapiro, a professor at the University of Chicago, is searching for a "third way," a scientific, non-Darwinian way. Shapiro maintains that five decades of genetic and molecular-biology research have transformed our vision of life. Ile compares the conceptual changes to those accompanying the transition from classical physics to relativity and quantum mechanics. This new theory of evolution -- his "third" way -- will emerge from the convergence of biology and information science. Genomes, asserts Shapiro, are not really the static "beads on a string" envisioned by the Darwinians. Rather, they are fluid and complex. Genes are now seen as multipurpose elements that turn on and off as required for the survival and well-being of the organism they belong to. In this paradigm-eroding paper (referenced below), Shapiro describes four categories of molecular discoveries that have revised our thinking about how evolution works: (1 ) Genome Organization; (2 ...
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... Science Frontiers ONLINE No. 135: MAY-JUN 2001 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Where Is The Maestro?As we learn more and more about the gene complements of our planet's multitudinous life forms, the more it seems that the vaunted genome may not incorporate all of the information necessary to construct a living organism. Despite assurances to the contrary, we must ask if we really know the whole story. These doubts manifest themselves as we see that creatures that are very much alike genetically may be radically different morphologically. In this vein, C. Ventner asserts that all higher vertebrates have roughly the same genes. The animals that result from these re-markedly similar genomes depend upon when specific genes are turned on and off. Ventner says, "We have the same number of genes as cats and dogs, but differently regulated." The genes themselves are supposed to be simply protein factories. Somehow, they are turned on and off (" expressing" themselves) in just the right sequences to help build the target animal. In a far-stretched analogy, the genes are the instruments in an orchestra and the proteins they produce are the notes in a symphony. But where are the symphony's score and its conductor? Very similar orchestras, it seems, can play radically different symphonies given different scores as interpreted by a maestro. Each living thing is likewise a symphony of proteins, each played by the genome at just the right time. But just where are the score -- ...
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... No. 135: MAY-JUN 2001 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Longevity And Sardinia If you were not born in the fall (see above item) and thereby received a few months' bonus in longevity, you might compensate for the loss by moving to sunny Sardinia in the Mediterranean. Nowhere else on the planet does a larger proportion of the male population live to the century mark. Strangely, female longevity is unaffected by whatever it is that produces the male Methuselahs. We have, therefore, two questions to answer: (1 ) Why do so many males reach the 100-year mark; and (2 ) Why are Sardinia's women short-changed? No one has good answers. It might be genetic (an inbreeding effect) or simply lifestyle (more imbibing of the island's red wine). (Koenig, Robert; "Sardinia's Mysterious Male Methuselahs," Science, 291:2074, 2001.) From Science Frontiers #135, MAY-JUN 2001 . 2001 William R. Corliss Other Sites of Interest SIS . Catastrophism, archaeoastronomy, ancient history, mythology and astronomy. Lobster . The journal of intelligence and political conspiracy (CIA, FBI, JFK, MI5, NSA, etc) Homeworking.com . Free resource for people thinking about working at home. ABC dating and personals . For people looking for relationships. Place your ad free. ...
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... , therefore, seem to be a bad evolutionary gambit. But, C. Koch and F. Crick may have an answer. They speculate that: It may be because consciousness allows the system to plan future actions, opening up a potentially infinite behavioural repertoire and making explicit memory possible. (Koch, Christof, and Crick, Francis; "The Zombie Within," Nature, 411:893, 2001.) Questions. Could our zombie agents, primitive though they may be, be the source of those flashes of genius that appear out of nowhere, or perhaps that "dreamwork" from which solutions to problems appear fully formed upon wakening? The quotation from the Nature article presumes that consciousness does have survival value, else it would not have evolved. What sort of highly innovative genetic changes would lead to such a remarkable brain function? Did consciousness evolve in small Darwinian steps or in some grand, lucky mutation? Did any nonhuman animals progress beyond their inheritance of zombie agents? From Science Frontiers #138, NOV-DEC 2001 . 2001 William R. Corliss Other Sites of Interest SIS . Catastrophism, archaeoastronomy, ancient history, mythology and astronomy. Lobster . The journal of intelligence and political conspiracy (CIA, FBI, JFK, MI5, NSA, etc) Homeworking.com . Free resource for people thinking about working at home. ABC dating and personals . For people looking for relationships. Place your ad free. ...
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... been grafted onto the Tree; namely, the archaea (microorganisms that look like bacteria but possess markedly different genes). The archaea favor extreme environments and, curiously, are more closely related to you and me than are the bacteria. But according to this article (by W.F . Doolittle), the triple-trunked Tree of Life is simplistic. One reason for this is that genes, once thought to flow only from parent to progeny, are now known to travel laterally. Species barriers are broken. Genes jump from trunk to trunk, from branch to branch, twig to twig. Of course, these jumps are seen primarily among the microorganisms. The real Tree of Life, then, is more like a snarl of vines--a Jungle of Life, a genetic Tower of Babel! Furthermore, no longer does the multiplicity of life forms spring from a single primordial cell but rather from a "common ancestral community of cells." Complicating the picture still further, many eukaryote genes are totally unlike those seen in the prokaryotes and archaea. They "seem to come from no-where." "Nowhere" might really be a fourth trunk supporting what is now seen as a confused tangle of vegetation. (Doolittle, W. Ford; "Uprooting the Tree of Life," Scientific American, 282:90, February 2000.) Comment. That "ancestral community of cells" could have been formed from more than one (nonsupernatural) creation and/or multiple infusions of life forms and/or biochemical templates conveyed to earth by comets ...
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... disparate properties of the 63 elements then known. Was there any pattern? One night he fell asleep and in a dream the elements fell into their proper places in the Periodic Table. (Mazzarello, Paolo; "What Dreams May Come?" Nature, 408:523, 2000.) Comments. These mammalian anecdotes involving sleep and dreams are amusing, but most dreams are frivolous, bizarre, and of very little practical value, Mendeleyev notwithstanding. The utility of sleeping and dreaming do not seem at all commensurate with the accompanying vulnerability and the loss of waking hours. However, speculation is fun. There are at least two rather far-fetched explanations for characteristics (sleeping and dreaming here) that do not appear to have very much survival value. Sleeping and dreaming may be linked genetically to a characteristic that does have considerable survival value. Example: Resistance to malaria is coupled to sickle-cell anemia. Sleeping and dreaming may represent unavoidable, intermediate, evolutionary steps toward something of much greater value. Example: those fea- thers on fossil dinosaurs; i.e ., the protobirds. Are sleeping and dreaming humans slouching toward Teilhard de Chardin's Omega Point or possibly A.C . Clarke's Childhood's End? From Science Frontiers #134, MAR-APR 2001 . 2001 William R. Corliss Other Sites of Interest SIS . Catastrophism, archaeoastronomy, ancient history, mythology and astronomy. Lobster . The journal of intelligence and political conspiracy (CIA, FBI, JFK, MI5, NSA, etc) Homeworking.com . Free resource for ...
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... Science Frontiers ONLINE No. 131: SEP-OCT 2000 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Will mtDNA Trump C14 and Projectile Points?Do not imagine for a minute that the Clovis Police are successfully suppressing all radical notions in archeology. Revolutionaries are everywhere. Not the least of these are studying the mtDNA (mitochondrial DNA) of Native American peoples and comparing it with the mtDNAs of Asians and Europeans. The geographical distribution of mtDNA haplogroups can trace out the migratory routes of early humans in the New World and, in addition, provide rough times-of-arrival. Some of this mtDNA evidence will undoubtedly attract the attention of the Clovis Police. But do these law enforcers -- mostly archeologists -- dare to challenge genetic data? Can mtDNA lie? There are in the cells of North American Native Americans mitochondria that seem to divide these peoples into four major "haplogroups." These four groups can be readily traced back to Siberia and northeast Asia. No trouble from the Clovis Police here! But there is also a "haplogroup-X " that does not fit the Clovis paradigm. In North America, haplogroup-X is found frequently among the Algonkian-speaking tribes, such as the Ojibwa. This same haplogroup occurs in Europe and the Middle East, especially Israel. It is notably absent in Asia. Furthermore, the data suggest that haplogroup-X was resident in North America thousands of years before the Vikings and Columbus made landfall. (Schurr, Theodore G.; "Mitochondrial DNA and the ...
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... of census records indicated that the situation was not quite as bad as Gompertz had supposed. Nevertheless, the death rate does increase with age; but we might be able to do something about it. Immortality might be achievable -- if we take recent medfly studies seriously. "Growing old does not increase your immediate risk of dying -- at least, if you are a fruit fly. The chances of a Mediterranean fruit fly ( Ceratitis capitata ) dying on a particular day reaches a peak and then declines, according to James Carey of the University of California at Davis and James Vaupel of Duke University, North Carolina, and Odense University in Denmark. Their results contradict the notion that the death rate rises with age in all species." The upshot is that there may be no genetic limit to an individual medfly's lifetime. And, if these results can be extended to humans, "then medical advances might eventually allow the elderly to live indefinitely." (Bradley, David; "Who Wants to Live Forever?" New Scientist, p. 16, November 14, 1992.) From Science Frontiers #86, MAR-APR 1993 . 1993-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 82: Jul-Aug 1992 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Can you guess where this quotation comes from?THE GRADUALIST'S DILEMMA "The basic article of faith of a gradualist approach is that major morphological innovations can be produced without some sort of saltation. But the dilemma of the New Synthesis is that no one has satisfactorily demonstrated a at the population genetic level by which innumerable very small phenotypic changes could accumulate rapidly to produce large changes: a process for the origin of the magnificently improbable from the ineffably trivial. This leads to skepticism about the microevolutionary approach. Perhaps, as Waddington put it: 'the real guts of evolution -- which is, how do you come to have horses and tigers, and things -- is outside the mathematical theory.'" Did you guess a creationist publication? Sorry! (Thomson, Keith Stewart; "Macroevolution: The Morphological Problem," American Zoologist, 32:106, 1992.) (And just the other day, we read that evolution was a proven fact!) From Science Frontiers #82, JUL-AUG 1992 . 1992-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 82: Jul-Aug 1992 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Big-bang brouhaha Unless you have been in a coma the past couple months, you have heard that the Big Bang has now been elevated from a theory to a fact. The reason for the media hullabaloo was the announcement that minute fluctuations had been detected in the cosmic microwave background. The media hype was notably chauvinistic. Some Big-Bang proponents declared that discovery was the greatest scientific advance of the century, completely ignoring the genetic code, continental drift, nuclear fission, and so on and so on. More sober scientists rejected such extravagant claims. They pointed out that independent confirmation of the fluctuations was yet to come and that, after all, the fluctuations were very small (only some 30 millionths of a K). And which of the many variations of Big Bang was going to be enthroned? Even Nature advised extreme caution, quoting H. Bondi in this regard: ". .. the data in cosmology are so likely to be wrong that I propose to ignore them." (Anonymous; "Big Bang Brouhaha," Nature, 356:731, 1992.) Comment. It is ironical that before astronomers found large-scale inhomogeneities in the cosmos (galactic clusters and superclusters, the Great Wall, etc.), the Big Bangers claimed that the very smoothness of the microwave background proved the reality of the Big Bang. The Big Bang, it seems, is one of those " ...
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... Science Frontiers ONLINE No. 77: Sep-Oct 1991 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Do birds use genetic maps during migration?Routes taken by migrating German and Austrian blackcaps en route to Africa. Hybrids bisect these initial paths and would end up in the Alps. Many young birds migrate successfully without help from older birds who have made the trip before. The implication is that migration instructions, perhaps even some sort of map of astronomical or geo graphical references, are somehow written upon the genes inherited from their parents. Just how maps can be coded into gene structure is anyone's guess. (In fact, since the DNA in the genes seems to cody only for protein synthesis, the locations and characters of inheritable maps and other biological instructions are not immediately obvious.) The problem has been exacerbated by recent experiments with German and Austrian blackcaps. These two common European warbler species take different routes to Africa in the winter. The Ger-man blackcaps fly southwest and the Austrian southeast--routes 50 apart. A. Helbig has crossed the German and Austrian blackcaps to see what route(s ) their hybrid offspring would take. Curiously, they favored a route intermediate between those of their parents. The hybrids' route -- bisecting those of the parents' -- would take the hybrids right into the Alps, where survival would be unlikely. (Day, Stephen; "Migrating Birds Use Genetic Maps to Navigate," New Scientist, p. 21, April 21, 1991.) ...
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... Science Frontiers ONLINE No. 74: Mar-Apr 1991 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects When Identical Twins Are Not Identical Past studies of identical twins separated at birth have documented remarkable similarities between them, despite the fact that they were reared under radically different circumstances. Their physical appearances, habits, vocations, health histories, and other factors are often eerily the same. For example, two female identical twins, who had never seen each other, each wore eight rings! The upshot of such investigations is that most of a person's characteristics are genetic in origin; that is, Nature dominates nurture. But what about identical twins who are remarkably different? They can, for instance, differ appreciably in size, intellect, and behavior. In such cases, does nurture dominate nature? No! Identical twins may diverge even in the womb, where one may receive more oxygen and nutrients than the other. One also may be assailed in by viruses, bacteria, or drugs, while the other escapes. Even more drastic is the possi bility that one twin may pick up an extra chromosome soon after the original egg has split. Also, mutations may doom one twin to Down's syndrome or some other genetic affliction, while the other is unscathed. Identical twins may even be of different sex! Of course, such twins are genetically different, but they are still monozygotic (from the same egg). Blood tests will show them to be identical. It used to be thought that the small ...
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... Science Frontiers ONLINE No. 66: Nov-Dec 1989 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Care for a cup of viruses?" The concentration of bacteriophages in natural unpolluted waters is in general believed to be low, and they have therefore been considered ecologically unimportant. Using a new method for quantitative enumeration, we have found up to 2.5 x 108 virus particles per millilitre in natural waters. These concentrations indicate that virus infection may be an important factor in the ecological control of planktonic microorganisms, and that viruses might mediate genetic exchange among bacteria in natural aquatic environments." (Bergh, Oivind, et al; "High Abundance of Viruses Found in Aquatic Environments," Nature, 340:467, 1989.) A sip of water could therefore introduce a billion virus particles into your stomach! This level of virus density in natural water is about 10 million times that formerly estimated. Besides reducing your thirst, what are the implications of this discovery? First, it suggests that bacteria in natural waters are probably kept in check by viruses as well as protozoans. So far, this sounds good. Second, since viruses can ferry genetic material between organisms via transduction (i .e ., host DNA is carried to the next host). This means that genes for antibody resistance and increased bacterial virulence (as present in sewage) may be spread quickly and widely. Also, "engineered bacteria" proposed for use in agriculture, viz., the ice-minus bacterium created to protect strawberries, ...
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... Science Frontiers ONLINE No. 66: Nov-Dec 1989 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Doubts About Two Ritually Recited Theories Do you think humans originated in Africa? We have heard for so long now that modern humans got their start in Africa. (This assertion is as hackneyed as: "Life began in a warm little pond"!) There is, of course, some evidence for the African claim. Studies of genetic material and the fossil record are suggestive, although the latter includes the Middle East as a possible birthplace. Other data, however, put the "founding group" of modern humans in Southeast Asia. The iconoclast here is C.G . Turner, II, an anthropologist at Arizona State University. He has analyzed secondary dental traits (number of roots, bumps, etc.) of 12,000 individuals from around the world - both ancient and modern. Turner believes that the "great web of humanity" originated in Southeast Asia. Since then, two large populations, each recognizable by their dental features, have evolved.: (1 ) northeast Asians and the ancient residents of the Americas; and (2 ) southeast Asians, Europeans, ancient Australians, and Africans. Also of note is the close resemblance between native Australians and Africans. (Bower, B.; "Asian Human Origin Theory Gets New Teeth," Science News, 136:100, 1989.) Did the eruption of Thera do in the Minoans? According to popular archeolo-gical doctrine, ...
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... No. 70: Jul-Aug 1990 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Killer Whale Dialects J. Ford is the curator of marine mammals at Vancouver's Public Aquarium. For years, he has been listening to killer whales converse as they hunt along the coast of the Pacific Northwest. About 350 whales in the area are divided into two communities, each of which is subdivided into several pods. Each pod has its own dialect of sounds used in communication. Some of the dia-lects are regional, like Bostonian or Texan; others are more divergent, like English and Japanese. This discovery promotes killer whales to the level of some primates and harbor seals. Usually, Ford says, the sounds made by animals are determined genetically. (Dayton, Leigh; "Killer Whales Communicate in Distinct 'Dialects,'" New Scientist, p. 35, March 10, 1990.) Reference. For more on killer whale communication, see BMT8 in our catalog: Biological Anomalies: Mammals I. To order, visit: here . From Science Frontiers #70, JUL-AUG 1990 . 1990-2000 William R. Corliss ...
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... their alleged occupants may be physically real. There are tens of thousands of people who think that they have observed something strange -- even after all hoaxes and misinterpretations of natural phenomena have been culled out. Most of those who are willing to accept UFOs as valid phenomenon think they are real hardware piloted by extraterrestrials. J. Vallee, a computer scientist and prolific writer on the subject, demurs, and he gives five reasons why: "( 1 ) Unexplained close encounters are far more numerous than required for any physical survey of the earth; (2 ) The humanoid body structure of the alleged 'aliens' is not likely to have originated on another planet and is not biologically adapted to space travel; (3 ) The reported behavior in thousands of abduction reports contradicts the hypothesis of genetic or scientific experimentation on humans by an advanced race; (4 ) The extension of the phenomenon throughout recorded history demonstrates that UFOs are not a contemporary phenomenon; and (5 ) The apparent ability of UFOs to manipulate space and time suggests radically different and richer alternatives." If not extraterrestrial hardware, what are the UFOs? Vallee has three suggestions: (1 ) they are "earth lights" a la P. Devereux; that is, an unappreciated terrestrial phenomenon that impresses mental images on the minds of observers; (2 ) They are artifacts of a "control system" operated by a nonhuman intelligence or, perhaps, a Gaia like manifestation of supernature (of which we are a tiny part) that is trying to modify our behavior; and (3 ) They are ...
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... .) The mussels get the oxygen they require from the ordinary seawater covering the dense brine. Like the biological communities surrounding the "black smokers" and other ocean-floor seeps, the brine-filled pockmark community includes several species of shrimp, crabs, and tube worms. We have here another example of the astounding ability of lifeforms to take advantage of unusual, even bizarre niches. (MacDonald, I. Rosman, et al; "Chemosynthetic Mussels at a BrineFilled Pockmark in the Northern Gulf of Mexico," Science, 248:1096, 1990.) Comment. Such examples of life's adaptability are so common one hesitates to label them as anomalous. Yet, one wonders how and why life acquired this property. Is the human urge to go to the planets a genetically derived extension of this urge to colonize new terri tories. From Science Frontiers #73, JAN-FEB 1991 . 1991-2000 William R. Corliss ...
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... , de Sarre sets out, in English, his basic thesis: Abstract. "The explanation of Man's special nature is to be sought in the original combination formed by a primordial brain, the globular form of the skull and initial bipedalism. The ape, when compared with Man, appears to be rather a vestige of Man's ancestral line than his predecessor, according to the views of Max Westenhofer, Serge Frechkop, Klaas de Snoo and Bernard Heuvelmans. The study of the human morphology allows logically to carry the problem of Man's origin back to a very early stage of the evolution, and not to which has been reached by apes. From chromosomal and DNA comparison in the cells of living apes and people, several researches argue to-day that humans are genetically more like the common ancestor than is either Chimpanzees or other apes. The array of facts and considerations should be sufficient for an unbiased mind to discount away any idea of simian antecedents in Man's ascent." The body of the article supports de Sarre's thesis with observations from embryogenesis, comparative anatomy (skull, hand, foot), and phylogenesis. (de Sarre, Francois; "Initial Bipedalism: An Inquiry into Zoological Evidence," Bipedia , 1:3 , September 1988.) Comment. Obviously, de Sarre is taking an extreme position, and any observations supporting his position are anomalous by definition. From Science Frontiers #65, SEP-OCT 1989 . 1989-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 63: May-Jun 1989 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Language Of Life Popular writers on biology are fond of saying that the genes and their DNA carry all information necessary for the development of an organism and the transfer of inherited characteristics. With the advent of the multibillion-dollar project to map the human genome (our genetic inventory), we have been seeing this extreme claim more often. The truth is that a map of the human genome will not tell us everything. By way of confirmation, we quote the lead paragraph from a recent article in New Scientist: "In the early days of molecular biology, during the 1950s and 1960s, scientists as much as journalists fuelled the euphoria that surrounded the cracking of the genetic code. The secret of life was revealed, so many people thought. As our understanding has grown, however, so has our awareness of our ignorance. Research at the forefront of the molecular sciences has shown that we can no longer regard DNA - the stuff of genes - as a direct and complete set of instructions for the synthesis of proteins. The evidence begins to suggest that messages in the DNA are, in themselves, no more precise than the symbols and sounds with which we communicate. As in the languages with which we are familiar, the correct sense of a message written in DNA seems to depend on the rigorous checking and correction of errors, and on the context in which they are read." The final sentence of the ...
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... Science Frontiers ONLINE No. 60: Nov-Dec 1988 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Purposeful evolution?One seemingly unassailable dogma of evolutionary biology insists that natural selection involves, first, the continuous, random, environment-independent generation of genetic mutations; and, second, the subsequent fixation of those mutations that are favored by prevailing conditions. In other works, the genetic mutations cannot be influenced by external events and conditions. But in recent experiments with bacteria (E . coli), J. Cairns et al, at the Harvard School of Public Health, find they actually do produce mutations in direct response to changes in their environment. The adjective "purposeful" has even been applied to the action of these bacteria! Can anything be more heretical? "One of the experiments involves taking colonies of E. coli that are incapable of metabolizing lactose and exposing them to the sugar. If the lactose-utilizing mutants simply arise spontaneously in the population and are then favored by prevailing conditions, then this would lead to one pattern of new colony growth. A distinctly different pattern is produced if, under the new conditions, the rate of production of lactose-utilizing mutants is enhanced. The observation is something of a mixture of patterns, indicating that directed mutation appears to be occurring. 'This experiment suggests that populations of bacteria...have some way of producing (or selectively retaining) only the most appropriate mutations,' note Cairns and his colleagues." (Lewin, Roger; "A Heresy ...
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... Science Frontiers ONLINE No. 64: Jul-Aug 1989 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Directed Mutation Dear reader, things have a way of working out serially. For several months, we have had in our possession a paper from Nature, by J. Cairns, of Harvard, plus some passionate correspondence stimulated by the paper. Now that the circle-forming sheep have provided a good introduction, we will jump into the fray, too. Basically Cairns (in Nature) and B. H. Hall (in Genetics ) say that organisms can respond to environmental stresses by reorganizing their genes in a purposeful way. Such "directed mutation" shifts the course of evolution in a nonrandom way. Such a conclusion was like waving a red flag in front of the evolutionists. R. May, at the University of Oxford, complained, "The work is so flawed, I am reluctant to comment." On the other side, a University of Maryland geneticust, S. Benson, comments, "Many people have had such observations, but they have problems getting them published." Our template in this discussion is an article by A.S . Moffat in American Scientist. She says, "The stakes in this dispute are high, indeed. If directed mutations are real, the explanations of evolutionary biology that depend on random events must be thrown out. This would have broad implications. For example, directed mutation would shatter the belief that organisms are related to some ancestor if they share traits. ...
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... Science Frontiers ONLINE No. 56: Mar-Apr 1988 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The fault, dear reader, is not in our stars but our pigs!Fred Hoyle, in his usual maverick style, has hypothesized that some human flu epidemics are caused by new viruses in jected into the biosphere from outer space. (See his book Diseases from Space .) In yet another book, Evolution from Space , he goes further, stating that the evolution of terrestrial life can also be affected by the extraterrestrial inoculation of genetic material. But, just maybe, influenza pandemics are due to pigs! Every 10-20 years, new flu viruses seem to crop up against which humans have little resistance. The latest theory is that there exists a human-duck-pig connection. It seems that human flu viruses can multiply in ducks, but are not transmitted among ducks. It is also likely that duck viruses multiply in humans, but are not transmitted from one person to another. But enter the pigs: "There is firm evidence that pigs can become infected by and may transmit both human and avian influenza viruses not only amongst other pigs but also back to the original hosts. Therefore, pigs seem to be 'mixing vessels' where two separate reservoirs meet and where reassortment between avian and human influenza A viruses occurs, giving rise to the antigenic shift by creating new human pandemic influenza strains with new surface antigens." The article stimulating this discussion worries about new aquaculture practices, especially in Asia ( ...
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... amino acids into selfreplicating structures; (2 ) slime-mold organization; and (3 ) the origin of the lens structure of the firefly. All of these claims are accompanied by computer simulations of self-organizing reactions. (Madore, Barry F., and Freedman, Wendy L.; "Self-Organizing Structures," American Scientist, 75:252, 1987.) Comment. While we believe that science is the best way yet discovered to search for truth, we have to admit that scientists sometimes get carried away in their zeal to explain things, especially with computer graphics. The Belousov-Zha botinskii reaction is certainly impressive. So is crystal growth. But are the atoms falling together to form a crystal analogous to soldiers falling into ranks; or the assembly of genetic information into the genotypes for our planet's multitudinous species? How far can we apply reductionism? Spectacular, evolving forms erupt in the Belousov-Zhabotinskii reaction. Waves of chemical activity propagate through a receptive liquid medium. From Science Frontiers #53, SEP-OCT 1987 . 1987-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 60: Nov-Dec 1988 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Anomalous Geographical Distribution Of Diabetes Mellitus The incidence of diabetes mellitus among children varies dramatically with geography. For children under 15, it is only 1.7 per 100,000 in Japan but rises to 29.5 in Finland. Within the States, it is 9.4 per 100,000 in San Diego and peaks at 20.8 in Rochester, Minnesota. Children of European descent in New Zea land contract it three times as often as Maori children. U.S . whites get the disease more frequently than blacks and Hispanics. "Causes of these 'extraordinary' distribution differences remain unknown .. .. Both genetic and environmental factors appear necessary for the disease." (Eron, C.; "Cold Facts on Diabetes," Science News, 134:117, 1988.) From Science Frontiers #60, NOV-DEC 1988 . 1988-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 40: Jul-Aug 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Genetic code not universal!Most current textbooks pronounce that the genetic code is not only universal to life but that it must. Alterations in the code, the reasoning goes, would garble genetic messages. Such dogma, however, is based on another dogma, which states that all life on earth derives from a single ancestral line in which the genetic code is fixed and has always been fixed -- a "frozen" accident hit upon "by chance" on the primitive earth. Recently, though, small deviations from the code have turned up in ciliated protozoons and mycoplasmas, much to everyone's surprise. (Scott, Andrew; "Genetic Code Is Not So Universal," New Scientist, p. 2l, April 11, 1985.) Comment. No major deviations from the standard genetic code have been found; but then no one has really looked, because everyone knew the code was universal. It would be quite a shock if terrestrial life were found to have several genetic foundations and as many schemes of evolution. From Science Frontiers #40, JUL-AUG 1985 . 1985-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 41: Sep-Oct 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Genetic Garrulousness It is tempting to predict that those cells with the most genetic material will belong to the most advanced organisms. One would, for example, expect to find more DNA or nucleotide pairs in human cells than the cells of bacteria or plants. In the case of the bacteria, this expectation is realized. Some plants, however, have one hundred times more DNA per cell than humans. Some fish and salamanders do, too. One reason why there is no simple relationship between a cell's genetic complement and the organism's complexity is that a lot of genetic material is apparently useless, with no known functions. Human genes, by way of illustration, possess about 300,000 copies of a short sequence called Alu. The Alu sequences seem to be simply dead weight -- functionless -- yet continuously reproduced along with useful sequences. One purposeless mouse gene sequence is repeated a million times in each cell. (Stebbins, G. Ledyard, and Ayala, Francisco J.; "The Evolution of Darwinism," Scientific American, 253:72, July 1985.) Comment. Why so much redundance? Or is there some purpose for this excess genetic material that we haven't yet descried? The "useless" sequences may merely be left over from ancient gene shufflings; or they may be awaiting future calls to action. The above tidbits come from a long review article that is ...
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... Science Frontiers ONLINE No. 41: Sep-Oct 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Evolution's motor runs fast and quietly M. Kimura has been promulgating what he terms The Neutral Theory of Evolution. He concludes that "the most prev-alent evolutionary changes that have occurred at the molecular level, that is in the genetic material itself, since the origin of life on Earth are those that have been caused by random genetic drift rather than by positive Darwinian selection." Kimua maintains and can experimentally prove to some extent that the genetic material of all organisms changes rapidly and constantly. The genes change much more rapidly than scientists believed just a few years ago. We observe few if any changes at the phenotype level (organism morphology) because the overwhelming majority of these changes are neutral. They confer no significant advantage or disadvantage on the organism. In fact, Kimura and others have demonstrated that the fastest molecular evolution occurs in the least important genes. It is fastest of all in the pseudogenes or dead genes, which seem to have no discernable functions. In other words, the genetic engine is running, but the gears are in neutral! In Kimura's thinking, these molecular changes may eventually become important at the phenotype level if the environment changes or there is some other destabilizing influence. Kimura is the author of the 1983 book The Neutral Theory of Molecular Evolution. Although Kimura has some experimental support, his theory is not widely accepted. (Motoo Kimura; "The Neutral Theory of Molecular ...
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... Science Frontiers ONLINE No. 39: May-Jun 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects How Animals Might Get Inverted The above title is just a literary ploy. We don't know how upside-down animals get that way; and, obviously, we don't think anyone else does either. Nevertheless, biologists are now discovering some radical things about life that could lead to some real "answers." First, we have a case of genetic material being transferred from a fish to a bacterium. The case at hand is the light-producing bacterium that provides the ponyfish with its luminous organ. In this symbiotic arrangement, the fish somehow passes genetic instructions to its retinue of bacteria. (Lewin, Roger; "Fish to Bacterium Gene Transfer," Science, 227:1020, 1985.) Comment. Perhaps symbiotic relationships are fine-tuned by the mutual exchange of information! Second, the role of viruses in transferring genetic material across species barriers is at last getting some serious attention. (Remember how Fred Hoyle was snickered at for promoting this idea in his books?) D. Erwin and J. Valentine, of the University of California, are now pointing out how a whole colony of "hopeful monsters" might be created en masse by an attack of viruses carrying new genetic blueprints. (And remember how Richard Goldschmidt got the same treatment as Fred Hoyle for suggesting "hopeful monsters" decades ago? (Anonymous; "Gene-Swapping Breaks Barriers in Evolutionary Theory," ...
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... Science Frontiers ONLINE No. 45: May-Jun 1986 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Scant Ant Chromosomes The Australian ant Myrmecia pilosula, called the "bulldog ant" because of its viciousness, carries all its genetic information in a single pair of chromosomes. (Males are haploid and have just one chromosome.) Although classified as a "primitive" ant, the bulldog ant exhibits complex social behavior and is obviously far from a simple biological entity. Biologists were therefore surprised to find all genetic instruction residing in a single chromosome pair. Social insects tend to have higher chromosome numbers. It is also interesting that Myrmecia pilosula, originally described as a single species, actually consists of several distinct sibling species with chromosome numbers (i .e ., pairs) of 9, 10, 16, 24, 30, 3l, and 32. Yet, they all look pretty much alike. (Crosland, Michael W.J ., and Crozier, Ross H.; Myrmecia pilosula, an Ant with Only One Pair of Chromosomes," Science, 23l:1278, 1986.) Comment. Chromosome number or the sheer quantity of genetic material seems poorly correlated with biological complexity. From Science Frontiers #45, MAY-JUN 1986 . 1986-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 41: Sep-Oct 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Scrapie Transmitted By Prions Scrapie is an infectious neurological disorder in sheep. The infectious agent has been isolated, but it consists only of geneless prions. Somehow, these prions, which are merely protein filaments, get into a sheep's brain and replicate themselves to cause scrapie. With no genetic material of their own, how do the prions multiply? Recent laboratory work suggests that the prions subvert a gene that normally dwells in the brain. With the help of this gene, an endless stream of prions emerges, and the animal is sick. In hamsters, which are employed in laboratory research on scrapie, a gene demarcated PrP has been implicated in scrapie. PrP is present in both healthy and infected hamster brains, but no one knows what its normal function is, if indeed it has one. (Anonymous; "Prion Gene," Scientific American, 253:60, July 1985.) Comment. One can make an immediate connection between the traitorous PrP genes in the hamster brains and the excess genetic material in humans and all life forms. Biologists commonly call excess genetic material "nonsense DNA" which only means that they haven't devined its purpose. But, as already sugested, these unused blueprints may have had some past purpose or will be called into action in the future. The purpose may be insidious, as in the case of scrapie, or vital to the organism's survival in some ...
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... like eye-brain systems through "convergent evolution"; or 2. The fruit bats inherited their eye-brain system from closely re lated primates and then developed flight through "convergent evolu tion." R.D . Martin, a physical anthropologist and author of this article, has reviewed the morphological characteristics of the fruit bats and primates. On this basis, he doubts that the fruit bats are pri-mates. Furthermore, molecular studies are also negative. Therefore, possibility #1 above is the more likely one. (Martin, R.D .; "Are Fruit Bats Primates?" Nature, 320:482, 1986.) Comment. In either case, #1 or #2 , we must acknowledge convergent evolution and the likelihood that some subroutine in the genetic code repeats itself in divergent species. Speculative as always, we must ask if the genetic instructions for human or even superhuman intelligence do not reside dormant-for-now in other species. Reference. For more on megabat similarities to primates, go to BMC4 in the catalog volume: Biological Anomalies: mammals II. Ordering information here . An epaulleted fruit bat. (Adapted from the McGraw-Hill Encyclopedia of Science and Technology) From Science Frontiers #46, JUL-AUG 1986 . 1986-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 48: Nov-Dec 1986 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Cosmic Chemistry Of Life C. Ponnamperuma, at the University of Maryland, speculates that the genetic code employed by earth life may, in fact, reflect a universal chemistry. His lab data "suggest that the formation and linking of life's building blocks -- amino acids and nucleotides -- may have been all but inevitable, given the starting chemistry of earth's 'primordial soup.'" Going even further Ponnamperuma believes that "if there is life elsewhere in the universe, chemically speaking it would be very similar to what we have on earth." (Raloff, J.; "Is There a Cosmic Chemistry of Life?" Science News, 130:182, 1986.) From Science Frontiers #48, NOV-DEC 1986 . 1986-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 40: Jul-Aug 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Most Profound Discovery Of Science This is what one scientist calls Bell's Theorem. Certainly not all scientists would agree with such an absolute declaration. Since Bell's Theorem lurks in the fog-shrouded country of quantum mechanics, most biologists probably haven't even heard of it. In any event, they would probably think the discovery of the genetic code more profound. Why all the fuss over Bell's Theo-rem? In the laboratory, Bell's Theorem is associated with an admittedly spooky effect: the measurements made on one particle affect the measurements made on a second, far-removed particle. In theory, the second particle could be on the other side of the galaxy, with absolutely no physical connection between the two -- unless you admit to spooky action-at-a -distance forces. (Some over-ly zealous think-tankers have even contemplated applying this effect to long distance, untappable, unjammable communications with submarines!) The article (referenced below) in which this apparent magic is discussed also dwells on another profundity associated with quantum mechanics: does that which is not observed exist? Einstein felt intuitively that it did; and one of his remarks on the subject led to this article's title. Unfortunately for Einstein, all recent laboratory experiments demonstrate that spooky actionat-a -distance forces do exist and that Einstein's intuition was incorrect. (Mermin ...
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... , accidentally pick up some fungus spores, and then fly off to true blueberry blossoms. The transferred spores infect other blueberry plants, causing them to produce white mummy-berries rather than blueberries. When spring comes round, the fungus-filled mummy-berries release the fungus to the leaves, and the cycle continues. (Anonymous; "A Fungus That Courts with Phony Flowers," Science 85, 6:10, September 1985.) Comment. The explanations usually served up for such remarkable adaptations are: (1 ) It is the product of chance and natural selection; and (2 ) The Creator made things this way. Are there not other possibilities? Perhaps the fungus somehow stole the blueprints for the flower from the blueberry's genome; i.e ., genetic endowment. After all, viruses are always subverting cell machinery. From Science Frontiers #42, NOV-DEC 1985 . 1985-2000 William R. Corliss ...
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... are involved in storing just one simple memory, the brain will quickly use up all available cells. It must be that individual brain cells can participate in the storage of many different memories. The conventional mem-ory-trace theory would have to be replaced by a new type of memory architecture. (Bower, Bruce; "Million-Cell Memories," Science News, 130:313, 1986) Comment. Our thinking about biological memory may be controlled by our preoccupation with the two-dimensional circuits of computer memories. Biological memories might be three-dimensional, or of even higher order. Some scientists have ventured that memory might entail electrical charge distribution patterns in the brain; such need not be limited to two dimensions. The same thinking can be applied to the storage of genetic information. While DNA, RNA, etc., may be pieces in the puzzle, the complete solution may include the ways in which these molecules are bent, twisted, convoluted, arrayed, juxtaposed, and so on. In a letter relating to the above article, P.J . Rosch points out that John's results are consistent with the holographic theory of brain function supported by Pribram and Bohm. "In a hologram, every element of the subject is distributed throughout the photographic plate, making it possible to reconstruct the entire original image from any portion of the picture. In this paradigm, the brain stores memory and deals with interactions by interpreting and integrating frequencies, retaining the data not in a localized area but dispersed throughout its substance." (Rosch, Paul ...
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... of the above paper also submitted a unique interpretation of the data by J.C . Stager. Stager begins by noting that the paper of Robbins et al has been criticized because the earliest known fossils of metazoans date back to only about 1 Gyr and, therefore, the supposed pellets were obviously something else. Sager next makes a giant conceptual leap: Quite clearly the data prove that feces evolved before animals did!! He goes on: "In standard systematic reasoning, one assumes that the most widespread characteristic represents the primitive state. The fact that feces look so much the same from individual to individual strongly suggests that feces are the primitive condition. The variety of animal bodies, on the other hand, implies that bodies are secondary or derived features of the organisms. The expansion of genetic research in the twentieth century has led to the conclusion among many geneticists that bodies exist solely for the propagation and dispersal of genes. This perspective has been dubbed 'the selfish gene theory'. While the author acknowledges the insight and creativity that went into the selfish gene theory, it must be pointed out that the idea has not been carried far enough by the geneticists. Where did the genes come from in the first place? Who ever heard of a sea bottom made up of DNA ooze? It is obvious from the fossil data that feces were teeming in the Precambrian oceans well before DNA appeared on the face of the earth, and that feces were therefore the original driving force of life. Bodies exist for the propagation and dispersal of feces, and genes are simply the instructions ...
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... Science Frontiers ONLINE No. 46: Jul-Aug 1986 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Music Of The Genes "S . Ohno has cracked a new genetic code. The 58-year-old geneticist doesn't have the whole thing worked out yet, but when he sets the genes to music -- or music to genes -- some strange and wonderful things occur. To wit: "The SARC oncogene, a malignant gene first discovered in chickens, causes cancer in humans as well. When Ohno translated the gene into music, it sounded very much like Chopin's Funeral March. "An enzyme called phosphoglycerate kinase, which breaks down glucose, or sugar, in the body revealed itself to Ohno as a lullaby." Seeing this item is from a newspaper, it was nearly consigned to the wastebasket. But wait a moment, Susumo Ohno is a Distinguished Scientist at the Beckman Research Institute of the City of Hope National Medical Center, Duarte, CA. Could there be something to it? Reading further; we find that Ohno believes that the structure of music seems to parallel that of the genes. He translates genes into music by assigning notes according to molecular weights. His ultimate goal is the discovery of some basic pattern (melody?) that governs all life. (Anonymous; "Scientist Tunes in to Gene Compositions," San Jose Mercury News, p. E1, May 13, 1986. Cr. P. Bartindale.) Comment. Not too long ago the ...
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... this figure has been raised ten-fold to 30 million species. Why the huge jump? For the first time, entomologists had found a way to efficiently sample the canopies of tropical forests. This rich stratum between the sunlight and gloomy forest floor 100+ feet below had been largely neglected before. The slick tree trunks and the attacking swarms of wasps and stinging ants deterred the insect counters. What the collectors did was to fire projectiles with ropes over the high branches and then haul up canisters of a knockdown gas. Insects rained down -- a cloudburst of new species -- neatly collected on sheets spread out below. Such techniques led to the 30-million figure. As Wilson put it, "The pool of diversity is a challenge to basic science and a vast reservoir of genetic information." (Wilson, Edward O.; "The Biological Diversity Crisis," BioScience, 35:700, 1985.) Comment. Are there other "hot spots of diversity" waiting to be discovered? Probably, but they will be under our feet, in the deepest waters -- places we do not frequent or suspect. We do know of an ancient mudbank that gave birth to multitudes of new and fantastic creatures. See below. From Science Frontiers #43, JAN-FEB 1986 . 1986-2000 William R. Corliss ...
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... the quantization of life!A recent article on the possible quantization of galaxies was placed immediately before an interview with S. Stanley, one of the proponents of punctuated evolution. Either fate or the mysterious forces of seriality seemed to be saying that it is now time to broach the subject of the quantization of life itself. The reader can blame Stanley only for the stimulus and his discussions of speciation and the discontinuous (quantized?) fossil record. (Campbell, Neil A.; "Resetting the Evolutionary Timetable," BioScience, 36:722, 1986.) Comments. When we suggest quantization in biology, two phenomena come to the fore: 1. The obvious splitting of life into well-defined states -- the species -- as defined morphologically and/or by the genetic code; and 2. The gaps in the fossil record, which imply a frequent lack of transitional forms from one species to another. As Stanley asserts repeatedly in his interview, the fossil record is actually quite good in many places, despite the long-voiced claims of the gradualists that transitional forms do not exist merely because of the deplorable state of the fossil record. In physics the analogous phenomena would be: (1 ) The chemical elements and their isotopes (or an atom's energy levels); and (2 ) The lack of transitional forms. Straining the analogy still further, the evolution of one species into another simply means that life-as-a -whole moves from one quantized state to another. There need be no transitional forms, just as there ...
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... Science Frontiers ONLINE No. 25: Jan-Feb 1983 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Promiscuous Dna The cells of plants (photosynthetic eukaryotes) are genetically the most complex that biologists have discovered. Each cell has three genetic systems: its own, that of the chloroplasts; and that of the mitochondria. It is supposed that the chloroplasts and mitochondria were once free-living cells that linked up with the embryonic plant cell to form a symbiotic partnership, with the host "plant" cell being the dominant member. Up until now, the three genetic systems were thought to be discrete, each going down its own pathway. But chloroplasts genes have now been found inside plant mitochondria, overturning conventional wisdom. To sum it all up, DNA seems promiscuous -- no respecter of privacy and breaking down all isolating genetic barriers. This discovery at once raises a dozen questions. For example, are mitochondria genes in chloroplast cells? How far does this promiscuity go? Can the same thing happen in higher organisms; say, with humans and symbiotic microorganisms or even not-so-symbiotic disease organisms? Is there no stopping this DNA? (Ellis, John; "Promiscuous DNA -- Chloroplast Genes inside Plant Mitochondria," Nature, 299:678, 1982.) From Science Frontiers #25, JAN-FEB 1983 . 1983-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 34: Jul-Aug 1984 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Dna Even More Promiscuous It was a surprise when DNA sequences from mitochondria in yeast cells were discovered setting up shop in the nuclear genomes (i .e ., the normal genetic endowment of the cell nucleus). Now biologists find that DNA sequences in many species regularly and frequently hop from one genome to another. Genetic material from cell chloroplasts mix with that of the mitochondria and that of the normal nucleus in what seems to be a free-for-all. This genome hopping has earned DNA the adjective "promiscuous." The significance of DNA promiscuity is to be found in the general belief that the cell's mitochondria and chloroplasts were once independent biological entities that, in the course of life's development, invaded or were captured by cells and have led a symbiotic life ever since. The mitochondria and chloroplasts perform certain important functions in the cell but were thought, until now, to retain considerable genetic independence. (Lewin, Roger; "No Genome Barriers to Promiscuous DNA," Science, 224:970, 1984.) Comment. The promiscuity of DNA raises speculation that other DNA-bearing entities that invade the body, especially the viruses, may transfer their DNA to the host, and conceivably vice versa. With DNA apparently much more promiscuous than believed earlier, the role of disease in the development of life takes on a new importance. In other words, all species can potentially exchange genetic ...
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... Science Frontiers ONLINE No. 28: Jul-Aug 1983 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Evolution By Numbers The following paragraph is taken from a letter to Nature by a "practising geneticist." "In the discussion in your columns about the application of quantitative methodology based on the study of evolutionary processes to the analysis of the development of human culture, there is an unquestioned assumption on both sides of that issue that quantitative theory, as expounded by practitioners such as Fisher, Haldane, Wright, Cavalli-Sforza and Maynard Smith, has been successful in illuminating and explaining the process of biological evolution and the genetic relationships between species. As far as I know, there is no evidence to support this assumption. Indeed, there is a vast number of observations unaccounted for in the extant quantitative evolutionary theories. Many of these observations (inducible mutation systems, rapid genomic changes involving mobile genetic elements, programmed changes in chromosome structure) challenge the most fundamental assumptions which these evolutionary theories make about the mechanisms of hereditary variation and the fixation of genetic differences." (Shapiro, James A.; "Evolution by Numbers," Nature, 303:196, 1983.) Comments. The "observations unaccounted for" are buried in such obscure journals as S.B . ges. Morph. Physio. (Munchen). It is pretty obvious that the Sourcebook Project is just scratching the surface. From Science Frontiers #28, JUL-AUG 1983 . 1983-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 29: Sep-Oct 1993 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Genes aren't everything Many species of birds show considerable variation in size, shape, and coloration in various parts of their ranges. Hithertofore, such geographical variations had been considered to be genetically controlled; that is, the genes also varied with the geography. But experiments in which the eggs of redwinged blackbirds were interchanged between nests in northern and southern Florida and also between Colorado and Minnesota seem to show that the environment is more important than genetic endowment. In the redwinged blackbird, the bill size and shape and body weight of the transplanted birds (after hatching, of course) were characteristic of the locale in which they were raised rather than that where the eggs were laid. (James, Frances C.; "Environmental Component of Morphological Differentiation in Birds," Science, 221:184, 1983.) From Science Frontiers #29, SEP-OCT 1983 . 1983-2000 William R. Corliss ...
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... Science, 221:568, 1983.) Also, men who have recently lost their wives to breast cancer have immune systems less responsive to mitogens. (Journal of the American Medical Association, 250:374, 1984.) (Maddox, John; "Psychoimmunology Before Its Time," Nature, 309:400, 1984.) Comment. This is an appropriate time to suggest that "psychoevolution" may be physiologically possible. If the brain can fight disease and even control cell growth, why not a role for the mind in stimulating the development of new spe cies, perhaps in response to extreme environmental pressures, and perhaps not on the conscious level? The body's sensory system would detect great external stresses, the brain would process the information, and direct some astute genetic shuffling. The genetic inheritance of an organism is not sacrosanct. Radiation, chemicals, and various others mutagens are recognized. There seems to be no a priori reason why the brainbody combination cannot generate mutagens -- possibly not randomly but intelligently! (We ignore here selfish DNA and Sheldrake's morphogenic fields.) Does this mean that if we wish to mutate, we can? Well, it's probably not as simple as wishing warts away, but Maddox's editorial underscores the complexity and subtlety of the brain-body combination. From Science Frontiers #35, SEP-OCT 1984 . 1984-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 37: Jan-Feb 1985 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The genome's responses to challenges The genome is an organism's genetic endowment. It contains instructions for the organism's growth and development, but it is not like a rigid, uncompromising computer program. Rather, the genome: ". .. is a highly sensitive organ of the cell that monitors genomic activities and corrects common errors, senses unusual and unexpected events, and responds to them, often by restructuring the genome. We know about the components of genomes that could be made available for such restructuring. We know nothing, however, about how the cell senses danger and instigates responses to it that often are truly remarkable." Thus Barbara McClintock ends the paper she delivered in Stockholm when she received a Nobel Prize in 1983. Most of McClintock's paper reviews her pioneering work with the corn genome, but she adds some examples of other genomic responses to external stresses. One such stress is applied to an oak tree when a wasp lays its egg in a leaf. The stress causes the oak genome to reprogram itself and construct a wholly new and unplanned plant structure to house and feed the developing insect. Some of these structures (galls) are very elaborate and are precisely tailored to each different wasp species. From such examples, it is apparent that the genome of an organism somehow perceives stresses and reacts to them -- often in completely unanticipated ways. The stresses may be mechanical, thermal ...
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... lizard actually developed from a membrane instead of cartilage. The two similarly located structures are not homologous after all. They had different origins. Superficially this doesn't seem very anomalous and especially not very exciting. But vertebrate evolution in particular has been charted on the basis of homologous structures. If these structures have different biological origins -- even in just some cases -- the evolutionary family trees may be drawn wrong. (Anonymous; "Lizard Bone Shakes World of Taxonomy," New Scientist, 98:221, 1983.) Comment. No one yet knows how serious this problem really is. Basically it means that some animals that look alike (at least bonewise) need not be closely related. To use an analogy, if nature has the plans for a house stored in genetic material, it may be able to build that house out of wood, brick, or what ever material is available. From Science Frontiers #28, JUL-AUG 1983 . 1983-2000 William R. Corliss ...
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... Science Frontiers ONLINE No. 22: Jul-Aug 1982 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects The Nomads Within Us It was originally believed that human chromosomes were fixed at conception and all subsequent organic development proceeded from the instructions encoded on them. Biologists have recently discovered that genes grasshopper about, constantly modifying genetic instructions -- at least that's the current thinking. Additional modification of genetic instructions seems to be accomplished by entities called "nomads" or "mobile dispersed genetic elements." One type of nomad is a simple ring of DNA called a plasmid. Plasmids seem to be identical to a kind of virus called a retrovirus, which can penetrate into cells and tamper with gene expression; that is, the way genetic instructions are interpreted. Plasmids have been discovered in maize, fruit flies, bacteria, and, now, humans -- and healthy people at that. No one is quite sure what these plasmids do. Even though they look like retroviruses, they may not be associated with illness, but rather help organisms adapt to changing environments. But no one really knows. (Anonymous; "Human Wandering Genes Can Live on Their Own," New Scientist, 94:18, 1982.) Comment. So, the human body is not only beset by new genetic instructions and the static introduced by invading viruses and other disease agents, but it has an indigenous population of nomads continually fiddling with our cells' genetic instructions. Our bodies seem more like Grand Central Station with trains loaded with new biological ...
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... Science Frontiers ONLINE No. 11: Summer 1980 Issue Contents Other pages Home Page Science Frontiers Online All Issues This Issue Sourcebook Project Sourcebook Subjects Hierarchies Of Evolution All organisms from man to mouse to amoeba are merely DNA's way of manufacturing still more DNA -- so goes the modern ramification of molecular biology and the Genetic Code. In other words, DNA and genes are selfish, and ultimate parasites, directing the evolution of life only to maximize the production of DNA. This theme is not the subject of this paper by Doolittle and Sapienza. Rather, they wonder about those nonsense DNA sequences that do not code for protein. The presence of these "useless" bits of genetic material is often explained in terms of gene "expression." Emphasis is always on maximizing the "fitness" of the organism (phenotype). Perhaps this seemingly excess genetic material actually maximizes the fitness (survivability) of the DNA itself. Evolution thus occurs at DNA and gene (genome) levels, despite what transpires at the organism (phenotype) level. (Doolittle, W. Ford, and Sapienza, Carmen; "Selfish Genes, the Phenotype Paradigm and Genome Evolution," Nature, 284:601, 1980.) Comment. We know that mitochondria and chloroplasts have their own genetic material; evolution may be occurring at this level, too, independent of pressures for change on the organisms. Waxing speculative, may there not be other hierarchies where systems are trying to maximize their own survivability, even at molecular, atomic, and subatomic levels? Don't laugh! ...
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